Survival Status and Predictors of Mortality on Maintenance Hemodialysis Among end-stage Renal Disease Patients in Governmental Hospitals Dialysis Centers at Addis Ababa, Ethiopia, 2021.
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Date
2021-06
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Addis Abeba University
Abstract
Background- End-stage renal disease is known to have been on the rise becoming public health concern globally. The disease worsened due to the presence of comorbidities conditions. The mortality rate and the reduced survival rate caused by the disease are still the highest. Hemodialysis is a common treatment option for end-stage kidney disease in Ethiopia It improves the quality of life, reduces morbidity, and prolongs patient survival. Objective -This study was aimed to determine the survival status and predictors of mortality among end-stage renal disease patients who undergone maintenance hemodialysis in Addis Ababa, Ethiopia, 2021. Methods- An institutionbased retrospective cohort study was conducted among end-stage renal disease patients who undergone maintenance hemodialysis between January 1st, 2014 and December 31st, 2019 using census sampling. The collected data were entered into epi data 4.2 and analyzed using STATA 14. Kaplan-Meier survival curve and log-rank tests were used to estimate the survival time and the presence of differences in survival among explanatory
variables. Cox regression was used at a 5% level of significance to determine the influence of each explanatory variable on outcome variables. Result -A total of 157 end stage renal diseases on hemodialysis patients were included
in the final analysis,of those37(23.6%)had died. The overall mortality rate was 7.9 years per 100 person-year. The overall estimated survival rate after the start of hemodialysis was 47.6% (95% CI: 30.6262.85%)
at 72 months follow-up. Diabetes mellitus (AHR, 3.1, 95%CI: 1.13-9.73),
baseline albumin level<3.5mg/dl (AHR, 3.2, 95%CI: 1.243-8.10), catheter (AHR, 3.56,CI: 1.60-7.93) were significant predictors of hemodialysis patients mortality. Whereas erythropoietin treatments were protective (AHR: 0.33). Conclusion and recommendation: The overall survival status of end-stage renal disease patients undergoing maintenance hemodialysis was found to be comparable with other international data.We reduced death of mortality should be emphasized to those with diabetes, low albumin level, catheter vascular type, and absence erythropoietin treatment
patients.
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Keywords
Chronic Kidney Disease, Hemodialysis, Mortality, Survival Status Time to Death