Impacts of Hiv Co-Infection and Mdr-Tb on the Treatment Outcome of Tuberculosis in Patients who Attended the two Shambu Health Centers In 2010- 2015.
| dc.contributor.advisor | Lakew, Mekuria (PhD) | |
| dc.contributor.author | Worku, Feyera | |
| dc.date.accessioned | 2018-06-28T12:47:01Z | |
| dc.date.accessioned | 2023-11-08T16:39:41Z | |
| dc.date.available | 2018-06-28T12:47:01Z | |
| dc.date.available | 2023-11-08T16:39:41Z | |
| dc.date.issued | 2017-08 | |
| dc.description.abstract | Tuberculosis (TB) is one of the major public health problems worldwide and typically attacks the lung. The disease has been later compounded with Multi-Drug Resistance TB (MDR-TB) and with a complex relationship between Human immunodeficiency virus (HIV) (TB/HIV co-infection. The problem is worse in Africa region, where our country is situated and the country is ranked 10th of the world’s 22 high burden countries. In Oromia Regional State the Case Detection Rate and Treatment Success Rate was 37% and 83% respectively. However, there is little information about TB in ShambuWereda (Western Oromia). To this end a retrospective study was made using secondary data collected from TB patients attending DOTs Clinic Service at Shambu Health Centers between2010-2015. The result showed that out 1364 TB patients, 54.84% were males and 45.16% were females with male to female ratio of 1.2:1; with a case detection of 30% smear positive (SPTB), followed by 49% smear negative Pulmonary TB (SNTB), 21 % extra-pulmonary TB (EPTB), and 0.36% MDR-TB cases. Although TB affects all age groups, the highest prevalence of 33.65% of TB occurred in the age group of 11-30; followed by 30% infection of the age group of 31-50 indicating that TB affected more than 6o% of the most active age groups. The prevalence of total TB patients slightly varied from year to year ranging from 15% -17.8% over the years with an average prevalence of 16.8% a steady prevalence of total TB in all the years without showing a trend of decrease along the years in spite of DOTS interventions in the area as a function of time. The prevalence of TB/HIV co-infection amongst all TB patients registered and screened for the same at the DOTs clinic was 18.8% with similar pattern of male to female infection of 1.3:1and similar pattern of 11% infection of the active age groups. The average treatment success rate (TSR) of TB cases was 72% and did not meet the WHO international updated targets of 85% for the period 2011 to 2015. It is yet a formidable task to achieve the same in the area, under the circumstances, with a new post-2015 Global TB Strategy called-End TB Strategy between 2015 and 2035 unless a serious DOTS intervention plan is introduced. Key words: Case detection rate(CDR),Extra Pulmonary Tuberculosis(EPTB),Smear Positive TB( SPTB),Smear Negative TB(SNTB), Treatment success rate(TSR), TB/HIV co-infection, MultidrugResistanceTB(MDR-TB) | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/4699 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Case detection rate(CDR), | en_US |
| dc.subject | Extra Pulmonary Tuberculosis(EPTB) | en_US |
| dc.subject | Smear Positive TB( SPTB) | en_US |
| dc.subject | Smear Negative TB(SNTB) | en_US |
| dc.subject | Treatment success rate(TSR) | en_US |
| dc.subject | TB/HIV co-infection | en_US |
| dc.subject | MultidrugResistanceTB(MDR-TB) | en_US |
| dc.title | Impacts of Hiv Co-Infection and Mdr-Tb on the Treatment Outcome of Tuberculosis in Patients who Attended the two Shambu Health Centers In 2010- 2015. | en_US |
| dc.type | Thesis | en_US |