Assessment of Cytopenias and Alse Eligibility Status af Apparently Healthy Blood Donors at National Blood Bank Services, Addis Ababa, Ethiopia
| dc.contributor.advisor | Zemenu Tamir | |
| dc.contributor.author | Biruk Hailu | |
| dc.date.accessioned | 2025-08-12T19:38:19Z | |
| dc.date.available | 2025-08-12T19:38:19Z | |
| dc.date.issued | 2022-06-16 | |
| dc.description.abstract | Background–Cytopenia occurs when one or more of your blood cell types are lower than it should be. Your blood consists of three main parts. Red blood cells, also called erythrocytes, carry oxygen and nutrients around your body. Objective: To assess the magnitude of cytopenias and false pass of apparently healthy blood donors and their associated factors at National Blood Bank Services, Addis Ababa, Ethiopia. Methods: A cross sectional study was conducted at national blood transfusion service (NBTS) from February to March 2020. Four hundred twenty one consented apparently healthy blood donors were recruited at national blood bank transfusion service and Socio demographic information were collected by using well-structured questionnaires through interview. Three ml blood samples were collected in EDTA tubes and analyzed using Beckman coulter (DxH) 800 automated hematology analyzer. Finally, the data was entered, cleaned and analyzed using SPSS version 23 statistical software. Descriptive statistics and Chi-Squared (X2) tests were used for statistical analysis. Result: In this study, a total of 421 apparently healthy blood donors were included. Among them 228(54.2%) were non-regular donors and 283(67.2%) males, were within the age group of 18-28 years 180 (42.8%).Among the blood donors,143(34%)of them were identified as falsely passed the donor selection criteria by the Copper sulphate gravimetric method and donated blood. False pass level was relatively higher among females, first time donors, older donors and those having normal ESR value. The prevalence of any cytopenia, anemia, leucopenia and thrombocytopenia were 153(36.3), 65(15.4%), 73 (17.3%) and 42(10 %,) respectively. Cytopenia was relatively higher among females, repeated blood donors, relatively advanced aged donors, donors with normal ESR value; though the difference did not show statistical significance (p≥0.05). However, cytopenia was significantly higher 93(65%) among blood donors who were falsely passed by the Copper sulphate gravimetric method of donor screening. Conclusion and recommendation: The study revealed higher level of falsely eligible blood donation and blood cytopenia among apparently healthy blood donors.Hence, we recommend large scale evaluation and consequent modification of the currently used donor recruitment criteria for the safety of both blood donors and patients. Keywords – hematological profile, blood donors, complete blood count. | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/6439 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | hematological profile blood donors complete blood count | |
| dc.title | Assessment of Cytopenias and Alse Eligibility Status af Apparently Healthy Blood Donors at National Blood Bank Services, Addis Ababa, Ethiopia |