Magnitude and Associated Factors of Intraoperative Laryngospasm Among Pediatric Patients who Undergo Surgery Under General Anesthesia at Tikur Anbesa Specialized Hospital,Addis Ababa.

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Addis Abeba University


Introduction: laryngospasm is a reflex closure of the upper airway due the glottis musculature spasm.It is one of the complications seen especially during induction of anesthesia or during emergence and its magnitude is high in pediatrics especially in infants.It may be due to patient-related associated factors like URTI, asthma, surgery-related associated factors like type of surgery and anesthesia-related associated factors like light anesthesia, type of airway device and type of anesthetic agent. Objective: To assess magnitude and associated factors of intraoperative laryngospasm among pediatric patients who undergo surgery under general anesthesia at Tikur Anbesa Specialized Hospital from December 5,2016 to April 13,2017. Methods:Institutional based cross sectional study design was conducted.Study participants were selected by systematic random sampling technique. Training was given for data collectors and supervisor. Regular supervision and follow up was made. Data was entered into Epi info version 7 computer software by investigators and was transported to SPSS version 20 computer program for analysis.Bivariate and multivariate logistic analyses were used to identify factors associated with laryngoscope. Statistical significance was sated at p value < 0.05 with 95% confidence interval. Result:A total of 143 study subjects were included. The overall magnitude was 21.7%.Neonates and infants were statistically associated with intraoperative laryngospasm (P value of .027 and .042 respectively).On the other handamong all cases which anesthetized by degree anesthetists,31.4 % (N=22) were developedlaryngospasm(P value of 0.025). Children who were induced by ketamine had less chance for laryngospasm.It had been found that pediatrics with light plain of anesthesia were three times more likely to have laryngospasm thanthose whose anesthesia was deep (P value 0.000,AOR 2.756(95% CI (0.867-8.754). Conclusion and recommendation-The result of the study indicated that the magnitude of laryngospasm in pediatric population was slightly higher especially during emergence phase. Therefore, appropriate measures should be taken by anesthetists to reduce the magnitude of laryngospasm.



Tikur Anbesa Specialized Hospital