Assessment of Health Related Quality of Life and Associated Factors Among Adult Patients With Epilepsy in Gamo Zone, Southern Ethiopia, 2023.

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Addis Ababa University


Background: Epilepsy has significant negative effects on a person's physical, psychological, and social well-being (Health Related Quality of Life). Education level, seizure type, seizure frequency, stigma, living situation, monthly income, medication adherence, side effects of antiepileptic drugs, and co-morbidity of mental disorders all significantly affect the quality of life of epilepsy patients, according to different studies. Objective: To assess Health Related Quality Of Life and associated factors among adult patients with Epilepsy in Gamo Zone, Southern, Ethiopia, 2023. Method: Institution based quantitative cross sectional study conducted on 252 participants from Feb 27 to Mar 27, 2023, at selected public hospitals. A simple random sampling technique was employed to select the required number of epileptic patients attending public hospitals in the Gamo Zone. Logistic regression model was used to identify the predictor’s health-related quality of life. The significant cut point was set to p-value < 0.05 at 95% CI. Result: From 259, a total of 252 epileptic patients participated in this study with the response rate of 97.2%. The mean total score of QOLIE-31 was 59.56 (SD=16.70). The highest mean (SD) score was the Cognitive function, 70.32 (SD=20.49) and the lowest was Seizure worry subscale, 42.2 (SD=23.95). 114 (45.2%) of the respondents scored below the mean in overall HRQOL. Factors associated with poor quality of life includes taking medications once per day [AOR=0.04; 95%CI (0.00-0.91)], having comorbid mental disorders [AOR: 4.53; 95% C.I (1.89- 10.86)] and encountering side effect of medications [AOR: 3.63; 95% C.I (1.74-7.55)]. Conclusion and Recommendation: HRQOL mean score of people living with epilepsy in Gamo Zone is low. Taking medications once per day, having comorbid mental disorders and experiencing adverse effect of medications associated with quality of life. This study recommends for health professionals, to improve the quality of life for epileptic patients, early detection of co-morbid mental disorders like depression and anxiety in those with epilepsy should be of utmost importance.



Health Related Quality of Life, Epilepsy, Seizure, Adult