Assessment of clinical presentation and outcomes sepsis among children admitted in pediatrics emergency department of Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia, 2019.
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Date
2019-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Addis Abeba University
Abstract
Introduction: Sepsis is life-threatening organ dysfunction caused by a deregulated host response
to infection. It is one of the leading causes of mortality among children worldwide. It is also the
second leading cause of death for 1-14 years of age and fourth leading cause of death for under
1 year of age. Appropriate and timely recognition of sepsis is a prerequisite for starting goaldirected
therapy
bundles.
Even
though
sepsis
is
common,
few
researches
are
done
in
the
area
of
study
and
the country.
Objectives: The study was conducted to assess the clinical presentations and outcomes of sepsis
among children admitted in pediatric emergency department of Tikur Anbesa specialized
hospital, Addis Ababa, Ethiopia.
Methodology: Institutional based retrospective chart review method had been conducted by
using standard checklist questionnaire for sepsis patients admitted in pediatric emergency unit of
Tikur Anbesa specialized hospital from January 1, 2017 to January 1, 2019. Data has been
checked, analyzed, and interpreted by using SPSS Software. The result was presented by tables,
bar charts and pie charts.
Result: A total of 305 sepsis patients were studied. Of this 3.9% and 2.9% were diagnosed as a
complication of sepsis which were sever sepsis and septic shock during admission. The most
common site of infection was chest focus accounted for (71%) of patients. The median value of
SIRS criteria was (IQR=2) and most patients (79.3%) were alert. From the total studied sepsis
patients, 13.4% have co morbidities. Majority of patients (81%) were started antibiotics more
than 1 hour after triage. About 55.1% of studied patients were discharge and 8.2% were death.
Of this, 3.6 %( n=11) of the death were within 48 hours.
Conclusion and recommendation: sepsis is significant concerning condition among children
due to its cause of mortality in the world. Majority patients had breathing problem; cardiac
concomitant diseases and majority were treated after one hour triage time in this study. As a
result every health providers should be awared for clinical presentations and treatments of sepsis.
Description
Keywords
Sepsis, pediatric, pediatric emergency, TikurAnbesa hospital