Magnitude and associated factors of Tracheal Intubation related adverse events in Pediatric Surgery at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia; 2019/20: Crosssectional Study
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Date
2020-06
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Addis Abeba University
Abstract
Background: Tracheal intubation is a rapid, simple, safe and non-surgical technique to achieve
airway patency, protects the lungs from aspiration and permits leak free ventilation during
ventilation while surgery is undergo. But it may associate with adverse events. Determining its
magnitude and associated factors are paramount in making smooth tracheal intubation.
Objective: To assess magnitude and associated factors of tracheal intubation related adverse
events in Pediatric surgery at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
Methods: Institutional based cross sectional study was conducted among 310 pediatric patients
who underwent surgery from December 30, 2019 to February 30, 2020 at TASH Addis Ababa,
Ethiopia. Systematic random sampling technique was used for selecting the study participants.
Prepared questionnaire was used for data collection. Variables that were found to be (p value of
< 0.25) on binary logistic regression entered into a multivariable logistic regression analysis to
identify independent predictors of tracheal intubation related adverse events. Level of statistical
significance was declared at p-value less than 0.05.
Result: During the study period, 310 intubations occurred in pediatric patients who underwent
operation room for pediatric surgery intubations were eligible for the study. In our study the
overall incidence of trachea intubation related adverse events among pediatrics patients who
underwent surgery was 36.5 %. Output of multivariable logistic regression revealed that, being
neonate (AOR of 4.134(1.266-13.498), emergency surgery (AOR of 3.392(1.415-8.132),
difficult intubation (AOR of 4.083(1.017-7.501)), intubation without using premedication (AOR
of 1.759(1.452-10.83)), intubation without using muscle relaxant (AOR of 1.811(1.103-8.142))
and trachea intubation attempted more than three (AOR 3.921(2.164-7.396)) were as
independent predictors of trachea intubation related adverse events
Conclusion and recommendations: The incidence of trachea intubation related adverse effect
in pediatric surgical patients is high. Being neonate, presence of difficult intubation, intubation
without using medication and paralytic drugs, emergency surgery, and multiple attempt of
intubation might be the predictors of tracheal intubation related adverse events. Anesthetist
should consider these factors during trachea intubation.
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Keywords
Magnitude, Trachea intubation related adverse events, Tikur Anbessa Specialized Hospital, Addis Ababa, Pediatric, Endotracheal intubation, operation room, and patient factors.