Anti- Retoviral Therapy Adherence among Hiv-Infected Children Aged 2-14 Years in Tikur Anbessa Sepcialized Hospital, Addis Ababa, Ethiopia
| dc.contributor.advisor | Mengistu Zuriyash | |
| dc.contributor.author | Diriba Ketema | |
| dc.date.accessioned | 2018-07-11T11:35:58Z | |
| dc.date.accessioned | 2023-11-06T09:01:45Z | |
| dc.date.available | 2018-07-11T11:35:58Z | |
| dc.date.available | 2023-11-06T09:01:45Z | |
| dc.date.issued | 2015-06 | |
| dc.description.abstract | Background: Adherence to antiretroviral therapy (ART) is a strong predictor of progression toAIDS and death. The fact that a nearly perfect adherence is required in ART has remained amajor challenge to people infected with HIV. Consequently, non-adherence to the proposed antiretroviral regimen is considered to be one of the greatest dangers to the response to treatment on an individual level and the dissemination of resistant viruses on the community level. Objectives: - The aim of the study was to identify the adherence level and associated factorswith adherence to ART among HIV infected children aged 2- 14 years in Black Lion SpecializedHospital ART clinic, Addis Ababa, Ethiopia. Method: - A cross-sectional study was conducted between April and May, 2015 in TikurAnbessa Specialized Hospital, Addis Ababa, Ethiopia. A total of 190 children aged 2-14 years onfirst line ARV regimen for at least six month were included in the study. The registered list of thechildren on ART by unique ART registration number was used as sampling frame. Data wascollected by using interview with structured questionnaire. Ethical clearance was secured fromAddis Ababa University College of health sciences institutional ethical review board. Thecollected data was cleaned, checked for quality, coded and analyzed by using manual andstatistical methods, logistic regressions were computed. Odds ratios were computed to determinethe level of significance. Result: A total of 190 children were included in this study, and 89.8% of the participants hadtaken their prescribed ARV drugs fully for the past 7 days. Considering individuals who had evermissed their dose regardless of time reference, overall adherence rate 87.75% was obtained.Although most frequently mentioned reason of missing their dose in the last one week wasforgetting (48.1%), ADRs, Quarrel among family are also found to be barriers to adherence.After controlling the effects of other variables, two variables namely income and occupation werefound to be significantly associated with adherence to ART in children. Conclusion: Adherence rate obtained in this study is lower than what is required. Forgetfulness,ADRs, and quarrel among family were most frequently mentioned barriers of adherence.Income and occupation are factors found to be significantly associated with adherence to ART inchildren | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/8019 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Tikur Anbessa Sepcialized Hospital | en_US |
| dc.title | Anti- Retoviral Therapy Adherence among Hiv-Infected Children Aged 2-14 Years in Tikur Anbessa Sepcialized Hospital, Addis Ababa, Ethiopia | en_US |
| dc.type | Thesis | en_US |