Clinico-pathology and Treatment Patterns of Urinary Bladder Cancer at Tikur Anbessa Specialized Hospital.
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Date
2022-02
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Addis Ababa University
Abstract
Back ground:
Bladder Cancer is the sixth most common cancer in the world, the seventh most common cancer in men, and the seventeenth most common cancer in women. Although the incidence of malignant tumors of the bladder is increasing in developing countries, like Ethiopia, there is a lack of evidence
regarding the overall profile of bladder cancer in Ethiopia.
Objective: To asses the demography, clinicopathology and treatment patterns of urinary bladder cancer attending at oncology department and Urology unit of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia during the study period.
Methods: An institution based descriptive cross-sectional study was conducted in TASH, department of Oncology and Urology unit, Addis Ababa, Ethiopia, and comprised medical records related to urinary bladder tumors between September 2018 and August 2021.
Results: Of 158 cases, 81% were of males while 19% were of females making a male to female ratio of 6.74:1. The mean age was 57.41±13.662 years (ranged from 22 to 88years). Hematuria was the most common presenting symptom occurring in 143 (90.5%). Transitional cell carcinoma
(urothelial carcinoma) was the most common histology which accounted 87.4% followed by Squamous cell carcinoma (6.3%), adenocarcinoma (1.9%), sarcoma (1.3%) and mixed histology variants (1.3%). Overall, 45.6% was non-muscle invasive, 37.3% was muscle invasive and the remaining 17.1%was metastatic at presentation. Majority of patients were treated with radical intent. TURBT was the most commonly practiced type of treatment. Intravesical chemotherapy, perioperative chemotherapy and cystectomy were rarely practiced as compared with standard guidelines and text books.
Conclusion: The most common type of bladder cancer in TASH is TCC. Bladder tumor is more frequent in men than in women. Hematuria was the most common presenting symptom. The commonest procedure for bladder tumors was TURBT which is the golden standard for nonmuscle invasive
tumors.
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Urinary bladder Cancer