Retrospective Analysis of Primary Oral and Maxillofacial Malignancy Patient Seen at Tikur Anbesa Specialized Hospital
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Date
2022-05
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Addis Ababa University
Abstract
Background; orofacial cancer is a malignant neoplastic proliferation of epithelial and
ectomesenchymal tissue of oral and maxillofacial origin. The late presentation of patient,
aggressive nature of orofacial malignancy and the anatomic site closure to vital organ make
orofacial cancer management challenging but no sufficient pioneer data in Ethiopia
Objective: to assess the patters of primary orofacial malignancy patient visited Tikur Anbesa
specialized hospital
Materials and Methods: consecutive cross sectional retrospective study was conducted on
175 patients diagnosed with primary oral and maxillofacial malignancy seen at, Tikur Anbesa
specialized Hospital over a period of January 2020 to December 2021. Data were collected
by chart review and entered to SPSS 25.0 for statistical analysis and results were presented
with table, figures and charts. Percentage and frequency were employed for categorical data
while mean was used for continuous variables.
Result: Of 175 primary orofacial case analyzed male were 57.1 %{ n=100} with male to
female ratio 1.48: 1, mean age of (48.21 ± 16.93 years) and range (12–91 years). Squamous
cell carcinoma was the commonest cancer (52.0%) followed by mucoepidermoid carcinoma.
About 34.% of patient had known risk factor. Majority of the patient were diagnosed as
stage IV, 65.7%. Distance metastases were identified in 8.6 % of the studied patient and
41.7% of patients were treated surgically.
Conclusion: The study showed as carcinoma was the most prevalent cause of orofacial
cancer. Majority of patients were presented with advanced stage of disease and surgery was
the main means of treatment modality.
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Keywords
Primary orofacial cancer, squamous cell carcinoma, sarcoma, stage