Incidence and Predictors of Post-Operative Paralytic Ileus After Major Abdominal Surgery at Selected Governmental Hospitals in Addis Ababa, Ethiopia, 2023/24: a Longitudinal study
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Date
2024-05
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Addis Ababa University
Abstract
Background: Abdominal surgery is one of the most common surgical procedures for patients with various diagnoses. Even though this surgery is widely performed for therapeutic and diagnostic purposes it is not free from complications. Of which postoperative ileus take the lion's share of contribution. Ileus is the functional inhibition of bowel activity. While it usually resolves within 2to 3 days, if it lasts longer than 3 days, it is considered as postoperative paralytic ileus. This study was conducted to assess the incidence and predictors of post-operative paralytic ileus after major abdominal surgery at selected governmental hospitals in Addis Ababa, Ethiopia.
Objectives: To Assess Incidence and predictors of post-operative paralytic ileus after major abdominal surgery at selected governmental hospitals in Addis Ababa, Ethiopia, from February 1– April 30, 2024
Method: A hospital-based multi-center longitudinal study was conducted from February 1 – April 30 2024 in major abdominal surgical patients. Once data was collected it was analyzed using Statistical Package for Social Sciences version 26. Binary logistic regression was run. Multivariate logistic regression was performed using factors with P < 0.2 in the bivariate analysis and of thoseP<0.05 was taken as independent predictors. The data was expressed as odds ratios and 95% confidence intervals.
Result: A total of 184 patients met the inclusion criteria. The incidence of Postoperative paralytic ileus was 14.1%. The median duration of postoperative paralytic ileus was 5 days. Electrolyte imbalance (AOR=4.154, 95% CI 1.363-12.660), smoking cigarette {AOR=3.729, CI (1.217-11.422), opioid intake (AOR=4.615, 95%CI 1.426—14.940) and total IV fluid intake(AOR=3.974, 95% CI 1.210-13.059) were statistically significant predictors of postoperative ileus.
Conclusion: Postoperative Paralytic Ileus commonly occurs following major abdominal surgeries.The risk of POI is increased in patients with electrolyte imbalance, in patients who take more than 3000ml of IV and >50mg opioid, and in cigarette smokers in selected governmental hospitals in Addis Ababa, Ethiopia
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Post-operative Paralytic ileus, Major Abdominal Surgery