The Relationship Between Dietary Folate Intake and Serum folate Status of Reproductive Age Women in Westgojjam, Ethiopia
| dc.contributor.advisor | Baye, Kaleab (Professor) | |
| dc.contributor.author | Bekele, Hawi | |
| dc.date.accessioned | 2021-01-27T09:39:45Z | |
| dc.date.accessioned | 2023-11-09T15:32:35Z | |
| dc.date.available | 2021-01-27T09:39:45Z | |
| dc.date.available | 2023-11-09T15:32:35Z | |
| dc.date.issued | 2019-07-07 | |
| dc.description.abstract | Folate is an essential nutrient, involved in several metabolic activity of the human body and it contributes to the prevention of neural tube defect. However, little is known about folate content of commonly consumed foods in Ethiopia. In addition research determining folate status among human subjects in Ethiopia is scanty. In WsetGojjam zone of the Amhara region, Ethiopia serum folate was determined in women of reproductive age (n=179). In addition, folate content of commonly consumed foods among participating households was determined. Furthermore, effect of traditional processing on the retention of folate content was investigated. Participating women had serum folate concentration of (26.8±5.8). Folate deficiency was found in 1.9% of the subjects. Staple crops from the households had folate concentration in the range of 4.4μg/100g (Maize) to 40.21μg/100g (Wheat). From legumes 9.7μg/100g (Pea) to 65.2μg/100g (Bean). The mean folate concentration of raw and cooked/baked food was 61.00 ± 13.7 Vs13.78 ± 3.9 (p=0.052) Most cereals and legumes are better source of folate. The result varies form 4-40μg/100g in cereals and 10-65μg/100g in legumes. Though, vegetables and fruits are folate-contributing foods, they are not frequently consumed in this area.Though, legumes and cereals are good source of folate in their raw form, their retention affected by different factors. There is a significant difference between raw food items and cooked ones in Shirowot. Whereas there is no significance difference between raw food items and cooked ones in Injera. This could be result of Tefbehavior which is Teff is a relatively good source of folate and fermenting it to Injera could increase its folate content. This could be a condition that favors folate production during fermentation. Almost all (95.4%) have optimal folate (>6.6ng/mL) in their blood, this shows that folate deficiency is not a public health problem. Also the result shows that there is no correlation between dietary folate intake and serum folate status. This could be due to some reasons like production of folate in the human colon, the method used to identify most frequent foods or because of serum usage for folate analysis. As recommendation, to have adequate folate intake these women should have diversified fooditems. And consume foods that are rich in folate like green leafy vegetables. Even diet alone cannot make the RDA to be met, so if possible fortified foods and supplements should be given. | en_US |
| dc.identifier.uri | http://10.90.10.223:4000/handle/123456789/24859 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Folate | en_US |
| dc.subject | NTD | en_US |
| dc.subject | Folate Deficiency | en_US |
| dc.subject | Reproductive Age Women | en_US |
| dc.subject | Injera | en_US |
| dc.subject | Shirowot | en_US |
| dc.title | The Relationship Between Dietary Folate Intake and Serum folate Status of Reproductive Age Women in Westgojjam, Ethiopia | en_US |
| dc.type | Thesis | en_US |