Magnitude and Associated Factors of Chewing Khat During Pregnancy and its Impact on Maternal, Pregnancy and Neonatal Outcomes in Eastern Ethiopia, 2022: Cross Sectional, Prospective Cohort and Histopathologic Study
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Date
2024-06-07
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Addis Ababa University
Abstract
Less is established about the maternal and fetal effects of chewing khat during gestation and hence, it is problematic to elaborate a robust evidence base on its effects. So far, a few reports exist which demonstrate the relationship between khat chewing and a few birth outcomes. In addition, these limited studies did not perform mediation analysis to explain how khat chewing affected the reported birth outcomes. Therefore, the present study is the first to demonstrate a model that clarifies how selected variables mediate the relationship between khat chewing during gestation and pregnancy outcomes, providing an explanation for how khat chewing during gestation can affect pregnancy outcomes. Additionally, to date there exists no attempt to demonstrate the effects of chewing khat during gestation on maternal, pregnancy and neonatal outcomes in a prospective cohort study design. More importantly, there exists no pervious attempt to demonstrate the effects of chewing khat during gestation on placenta and umbilical cord in histopathologic study approach.
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Chat/khat chewing, substance use/misuse/abuse, magnitude, prevalence, associated factors, perceived reasons, maternal outcomes, fetal development, pregnancy outcomes, birth outcomes, neonatal outcomes, Ethiopia