Synthesis, Antimicrobial, and In silico Studies of 2-Hydroxy-1,

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dc.contributor.advisorDaniel Bisrat
dc.contributor.authorTemesgen Kusse
dc.date.accessioned2026-06-22T15:50:12Z
dc.date.available2026-06-22T15:50:12Z
dc.date.issued2025-06-10
dc.description.abstractInfectious diseases place a significant impact on the healthcare system. It causes 7.7 million fatalities each year, with a disproportionately high burden in sub-Saharan Africa. Drug resistant pathogens attributed to 4.95 million are and 1.27 million are brought on by illnesses of bacteria that are resistant to the current medications. Therefore, there is an urgent need for new, safe, and effective compounds to combat antimicrobial resistance (AMR). In
dc.identifier.urihttps://etd.aau.edu.et/handle/123456789/8407
dc.language.isoen_US
dc.publisherAddis Ababa University
dc.subject2-Hydroxy-1
dc.subject2-diphenylethanone
dc.subjectAntimicrobial activity
dc.subjectIn-silico studies
dc.subjectDisulfide bond oxidoreductase (DsbA)
dc.subjectMannich reaction
dc.titleSynthesis, Antimicrobial, and In silico Studies of 2-Hydroxy-1,
dc.typeThesis

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