Factors associated with obstetrics mortality in intensive care unit of Addis Ababa public hospital in, 2020/2021. (A hospital based case control study)
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Date
2021-06
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Addis Abeba University
Abstract
Background: Obstetrics mortality in intensive care unit (ICU) is high in low income countries
like Ethiopia. The indications of admission are Preeclampsia/ Eclampsia, postpartum
hemorrhage, and puerperal sepsis but, patient outcomes subsequent to intensive care unit
admission are lacking.
Objectives: To assess factors associated with obstetrics mortality in ICUs’ of Addis Ababa
Public hospitals, Ethiopia from October 2020 – May 2021.
Methods: A hospital based unmatched case control study was conducted on obstetrics patients
admitted to Addis Ababa Public hospital’s intensive care unit from October 2018 to November
2020. Data from 75 cases (died) and 150 controls (survived) were collected using simple random
sampling technique. Multivariable logistic regression analysis was done; Odds Ratio and
Confidence Interval (OR and 95% CI) were computed using SPSS version 26. P value < 0.05
was taken as statistically significant.
Result: Obstetrics mortality in intensive care unit was high and accounts 27% from the total ICU
admission. Severe pre-eclampsia AOR: 6.33; 95% CI: 2.25-17.79, peurpral sepsis AOR: 4.51;
95% CI: 1.68-12.15, age greater than or equal to ( ≥ 35) AOR: 4.09; 95% CI: 1.42-11.77,
absence of antenatal care: AOR: 3.74; 95% CI: 1.03-13.5, maternal coexisting diseases AOR:
5.2; 95% CI: 2.22-12.16, and severe GCS at admission AOR: 3.78; 95% CI: 1.21-11.79 were
significantly associated with obstetrics mortality in Addis Ababa Public Hospitals intensive care
unit.
Conclusion and Recommendation: Advanced maternal age (≥35 years), loss of antenatal care,
peurpral sepsis, severe pre-eclampsia, pre-existing medical comorbidities and severe Glasgo
coma scale (GCS) during ICU admission were the most significant factors associated with
obstetrics mortality in intensive care unit. It is recommended that all pregnant women should
have antenatal care so that preeclampsia and maternal comorbidies will be early diagnosed and
treated.
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Keywords
Obstetrics mortality ,Intensive care unit ,Anesthesia