Patterns of Presentation and Management of Differentiated Thyroid Cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
| dc.contributor.advisor | Beyene Assefa | |
| dc.contributor.author | Kirubel Tesfaye | |
| dc.date.accessioned | 2025-03-20T14:30:50Z | |
| dc.date.available | 2025-03-20T14:30:50Z | |
| dc.date.issued | 2023-02-19 | |
| dc.description.abstract | Background: Thyroid cancer is one of the most commonly diagnosed endocrine malignancies around the world with the incidence still increasing. In spite of the increasing number of diagnosed cases, the mortality rate has stabilized or even decreased in some countries. This is achieved through the early diagnosis and implementation of effective modes of treatments. Objective: To assess the patterns of presentation and the management of differentiated thyroid carcinoma patients at Tikur Anbessa specialized hospital from December 2017 to December 2022. Methods: A Hospital based retrospective secondary data was used where 84 patients with the diagnosis of Differentiated thyroid cancer who attended endocrine surgical Unit of Tikur Anbessa Specialized Hospital from December 2017-December 2022 were included.. Results: 84 participants were enrolled in our study where their age ranges from 14 to maximum of 84 years, mean age was 44.5 ±14.8 years with a female predominance; male-to-female ratio of 1:1.9. Anterior neck swelling was the commonest presentation 58(69%) and risk factor 41(48.8%) for DTC . TNM stages 1&2 were the commonest presentation stages 59.9% with distant metastasis detected in 24(28.5%). Papillary thyroid cancer was detected in 63(75%) and follicular variant in 21(25%) of the cases. Total thyroidectomy was the commonest surgical procedure undertaken with 46.3%. Recurrence was detected in 26(30%). RAI therapy was indicated in 54(64%) cases. Conclusion: Most of the participants were females and anterior neck swelling was the commonest presentation pattern. Papillary thyroid cancer was the most prevalent cellular type and total thyroidectomy was the procedure of choice in most cases. Radioiodine therapy was indicated in the majority of cases. The detected rate of recurrence was not negligible. Key words: differentia | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/5214 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Ababa University | |
| dc.subject | differentiated thyroid carcinoma thyroidectomy radioactive Iodine therapy thyroid cancer Management | |
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| dc.title | Patterns of Presentation and Management of Differentiated Thyroid Cancer at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia | |
| dc.type | Thesis |