Survival Status and Predictors of Mortality Among Burn Patients Admitted to Intensive Care Unit at Burn Centers in Addis Ababa ,Ethiopia 2022/2023,Retrospective Cohort Study

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Date

2023-04-25

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Addis Ababa University

Abstract

A burn critical care unit is a serious global healthcare burden. Especially in low- and middle-income countries, the mortality rate of burn patients admitted to the ICU is higher. In industrialized countries, the ICU death rate for burn patients is also significant. There is limited information about mortality and its predictors in the ICU for burn patients. Hence, this study is designed to investigate the survival status of burn patients in the ICU and its predictors. Objective: This study estimate the incidence and predictors of mortality among burn patients admitted to intensive care units in Addis Abeba governmental hospitals, Ethiopia, from January 1, 2019, to December 30, 2022. Methods: An institution-based, multi-center retrospective cohort study was conducted on 422 newly admitted burn patients at the intensive care units of two Addis Ababa governmental hospitals from January 2019 to December 2022. A simple random sampling technique was used to select 422 patients. The data were entered into EpiData version 4.6, and analyzed with STATA version 17. A standard Cox regression model was used. Both bivariable and multivariable regression models were fitted to identify predictors of each outcome. The 95% confidence interval of the hazard ratio (HR) was computed, and variables which had p-value < 0.05 in the multivariable model were significantly associated with the dependent variable. Results: From the sample of 422 patients, 416 burn patients were followed retrospectively with a median follow-up time of 9 days and an IQR of 7–13 days. This study showed that the overall mortality rate was 149 (35.72%). Electrical burns(AHR:11.9(95%CI:5.73–31.4), full-thickness injuries (AHR:2.6(95%CI:1.72–4.05), inhalational injury(AHR:5.32(95%CI:1.6,17.8) were significantly associated with the mortality of burn patients admitted in the ICU. Conclusion and recommendation: The overall mortality of burn patients admitted in ICU high and predictors of mortality include depth injury, mechanism of injuries, mechanical ventilation age. More consideration is needed for patients who had full thickness burn injury, Inhalational injury and age < 5 years.

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Keywords

Burn, Mortality, survival status, ICU, Predictors

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