Antibacterial Activity of Moringa Stenopetala against Some Human Pathogenic Bacterial Strains
| dc.contributor.advisor | Mekonnen Yalemtsehay (Professor) | |
| dc.contributor.author | Chekesa Basha | |
| dc.date.accessioned | 2018-06-22T08:16:49Z | |
| dc.date.accessioned | 2023-11-08T16:39:18Z | |
| dc.date.available | 2018-06-22T08:16:49Z | |
| dc.date.available | 2023-11-08T16:39:18Z | |
| dc.date.issued | 2012-06 | |
| dc.description.abstract | An emerging of antibiotic resistance brings most serious public health problems. It is therefore, important to look for more effective, safer and less toxic alternate options of treatment. The aim of the present study was to investigate antibacterial activity of Moringa stenopetala against some human pathogenic bacteria using disk diffusion method and agar dilution for minimum inhibitory concentration. The result revealed that, most of the plant extracts had antibacterial activity. Staphylococcus aureus was found to be the most susceptible bacteria to crude 80% methanol extract of seeds and ethyl acetate extract of root barks with inhibition zones of 18.66±0.88mm and 16.00±1.15mm and minimum inhibitory concentration of 1.25mg/ml and 2.5mg/ml respectively, whereas Pseudomonas aeruginosa was the most resistant bacteria to all of crude extracts. Similarly, Staphylococcus aureus was the most susceptible bacterial strain to chloroform fraction with inhibition diameter of 28.00±0.57mm and minimum inhibitory concentration of 0.31mg/ml, while Pseudomonas aeruginosa was the most resistant strain with inhibition zone of 9.66±0.33mm and minimum inhibitory concentration of10mg/ml respectively. In conclusion, this study is not only proves antibacterial activity of Moringa stenopetala, also provides a scientific basis for their traditional use. Pure chemical compounds and antimicrobial activity against many fungi and bacteria should be studied to use them as sources and templates for synthesis of drugs to control infectious diseases. Key words and phrases: Antibacterial activity, Moringa stenopetala, traditional medicine, extracts, fractionation, MIC, solvents | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/2923 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Antibacterial activity | en_US |
| dc.subject | Moringa stenopetala | en_US |
| dc.subject | traditional medicine | en_US |
| dc.subject | extracts | en_US |
| dc.subject | fractionation | en_US |
| dc.subject | MIC | en_US |
| dc.subject | solvents | en_US |
| dc.title | Antibacterial Activity of Moringa Stenopetala against Some Human Pathogenic Bacterial Strains | en_US |
| dc.type | Thesis | en_US |