Defaulting from Dots and its Determinants in Three Districts of Arsi Zone, Oromia Regional State, Ethiopia.
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Date
2000-12
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Addis Abeba Universty
Abstract
A case-control study, on defaulting From DOTS was performed in three districts of ArsiZone, Oramia Regional State, among patients registered during the period of July I, 1997 to December 31 , 1999 to determine the rate of defaulting and to identify factors associated with it. A health record review of 1367 new tuberculosis patients put on DOTS during a period of 30 months (July 1997 to December 1999) was carried out in order to determine the rate of defaulting. All the study subjects were registered and put on DOTS after June 30, 1997 and completed treatment or declared cured before January 1, 2000. The cases and controls were traced actively and interviewed by trained interviewers using a pre-tested structured questionnaire. The two groups were compared by social, demographic and health services variables. The overall defaulter rate and specific rate by month of defaulting, health institutions, distri cts and distance from health institutions were calculated. All defaulter sand the non-defaulters were selected by paired matching of sex and age using the lottery method. Two controls were matched individually to each case. One hundred fifty five cases and one hW1dred sixty controls were included in the study. The overall defaulting rate froID DOTS was calculated to be 11.3%. The rate of defaulting in case of sputum smear positive pulmonaty tuberculosis was found to be 11 .6%. The rate of defaulting was higher in Etheya clinic and Hitosa District. Highest (80%) rate of defaulting occurred during the continuation phase. Medication side effect was found to be significantly associated with defaulting from DOTS (OR= 4.20 with 95% CI 1.51 to 11.66).Adequate knowledge and family Support were found to be important possible protective factors for defaulting (OR=0.04 with 95% CI 0.02 to 0.10 and OR=0.19 with 95% CI 0.08to 0.46 respectively). Distance from health units and drug intolerance were the major reasons mentioned for defaulting. However, there is no significant difference between cases and controls regarding distance, employment status, attitude to treatment center, level of education and average monthly income. The rate is slightly higher than tlle critical level of 10% set by WHO. The major factor scontributing to high rate of defaulting were lack of family Support, inadequate knowledge about duration of treatment and presence of medication side effects. Health programme that are intended to enhance family support and knowledge about duration of DOTS treatment and Drug tolerance should be strengthened.
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Keywords
Defaulting,Dots