Girl’s Preference for Human Papilloma Virus Vaccination in secondary schools in Addis Ababa, Ethiopia, 2017: Discrete Choice Experiment
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Date
2017
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Addis Abeba Universty
Abstract
Background: There are three HPV vaccines that are safe and effective for protecting HPV
infection. These are: bivalent which protect from HPV type 16 and 18, quadrivalent for HPV type
6, 11, 16 and 18, and nonavalent for HPV type 6, 11, 16, 18, 31, 33, 45, 52 and 58. About 7,000
new cervical cancer cases are diagnosed annually in Ethiopia. It is the second cause of cancer
related death in women aged 15 to 44 year. Even thouge Ethiopia undergo a pilot for HPV vaccine
implementation at two sites in Oromia Region, Jimma zone, Gomma woreda and Tigray Region
Ahiferom Woreda with support of GAVI, there is no data that show a finding regarding the current
status of receiver’s attitude, acceptance, and mainly girls’ preference for HPV vaccine.
Objective: The aims of this study was to rank the contribution of the attributes for HPV
vaccination; and to measure the willingness-to-pay, the trade-offs, and choices of girls between
risk and benefits of the vaccination.
Methods: The study was done by using discrete choice experiment (DCE). The data was collected
from Februray to March 2017 among 4 different secondary schools in Addis Ababa. A total of 336
girls aged 15-18 year were included in the study. The vaccination program attributes considered in
the choice experiment were: degree of protection against cervical cancer, duration of protection,
age at vaccination, number of doses, risk of developing serious side effects, price of vaccine, and
way of delivery. Each choice set of all determined options were put in to mixed logit model to
determine the sign of the coefficient of each attributes. Trade-offs and WTP also determined.
Results: From all participants, only six of them had been vaccinated for HPV. Doctors
recommendation (34.9 %), mass-media campaign (81%) and positive familys’ opinion (80 %) were
factors encouraging respondents to get the vaccination. Girls were willing to trade-off 5 % of
protection against cervical cancer in order to get HPV vaccination which had protective duration
of 25 years instead of 8 years. On average the respondents were willing to pay 153 ETB for an
improvement in protection against cervical cancer from 70 % to 98 %.
Conclusion: There was significant variationeof preference among girls for all HPV vaccine
attributes. Degree of protection, number doses, and the risk of serious side effect were the three
most important attributes which guide the choice of girls, while cost of the vaccine had been the
least important factor. We found high level of tradd-offs level of protection against number of
doses, seriouse side effects and place of delivery
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Keywords
Girl’s Preference for Human Papilloma