Prevalence of Hiv Seroreactivity in Anogenital Wart Patients at ALERT, Addis Ababa, Ethiopia: A Prospective Study
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Date
2024-12-05
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Addis Ababa University
Abstract
Anogenital warts (AGWs) are visible warts seen in the body's perigenital and perianal
regions(1). They are benign lesions caused by HPV types 6 or 11 which are low risk (LR)
types, with the remaining 10% caused by a co-infection with high risk (HR) types(1–3).
In addition to epidemiological evidence, biological findings confirm the mechanisms for
sexually transmitted infections (STIs) increasing Human Immunodeficiency Virus (HIV)
acquisition and transmission via direct mucosal disruption, recruitment of HIV target cells to
the genital tract, and increased HIV load in plasma and genital secretions(8).
Immunosuppression, on the other hand, is a key risk factor for chronic human papilloma
virus (HPV) infections and, as a result, the development of HPV-induced lesions. The
frequency and prevalence of benign and malignant HPV-induced anogenital lesions are much
higher in HIV-infected patients
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Keywords
Prevalence of HIV Seroreactivity