The Association Between Low Maternal Serum Magnesium and Calcium Levels with Preterm Delivery and Low Birth Weight; in East Gojjam Zone, Amhara, Ethiopia
| dc.contributor.advisor | Muluken Walle | |
| dc.contributor.author | Hailay Kiros | |
| dc.date.accessioned | 2026-03-07T08:18:24Z | |
| dc.date.available | 2026-03-07T08:18:24Z | |
| dc.date.issued | 2025-02-01 | |
| dc.description.abstract | Background: Micronutrients like magnesium and calcium have a significant impact on the health of pregnant women and the growing fetus. They are involved in protein synthesis, bone matrix development, energy metabolism, regulation of muscle contraction, and hormone secretion. The deficiency of these micronutrients in pregnant women could be associated with adverse birth outcomes like low birth weight and preterm delivery. However, their association with preterm delivery and low birth weight in Ethiopia has not been determined. Objective: To determine the association between maternal serum magnesium and total calcium levels with preterm delivery and low birth weight in East Gojjam Zone, Amhara, Ethiopia. Methods: An institutional-based cohort study was conducted among 196 pregnant women with preterm births (24), term births (172), normal birth weight (168) and low birth weight (28) from June 2019 to December 2020. A questionnaire adopted from EDHS and FIGO was used to collect data on the socio demographic characteristics, anthropometric and obstetric conditions of pregnant women. 5ml of blood was collected and the maternal serum Mg2+ and Ca levels were measured using a chemistry analyzer; UniCel Dxl. All statistical data were performed by using SPSS version 25.0. Independent t test was used to compare the means of magnesium and calcium levels between the groups. Binary logistic regression was used to predict the occurrence of preterm delivery and/or due to hypomagnesemia and/or hypocalcemia. A P-value < 0.05 was used to declare statistical significance. Results: The mean ± SD age of the study participants was 25.98 ±4.37 (range:16-38). The majority were married (99%), between 21-30 years (73.0%), house wives (41.3%), had completed senior secondary education (31.3%) and live in urban areas (85.8 %) with medium income (45.5%). Moreover, more than half of the participants (52.6%) were primigravida. The prevalence of PTD and LBW in the study population was 12.2 % and 14.28 % respectively. Maternal serum magnesium level was significantly associated with preterm delivery (t=-6.323, P | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/7922 | |
| dc.language.iso | en | |
| dc.publisher | Addis Ababa University | |
| dc.subject | :Preterm delivery | |
| dc.subject | Low birth weight | |
| dc.subject | Magnesium | |
| dc.subject | Calcium | |
| dc.title | The Association Between Low Maternal Serum Magnesium and Calcium Levels with Preterm Delivery and Low Birth Weight; in East Gojjam Zone, Amhara, Ethiopia | |
| dc.type | Thesis |