“Clinical Characterization, Detection of Canine Parvovirus and Bacterial CoInfections, and Evaluation of Treatment Outcomes in Clinically Suspected Puppies at AAUCVMA Veterinary Teaching Hospital, Bishoftu, Ethiopia
| dc.contributor.advisor | Abdi Feyisa | |
| dc.contributor.advisor | Bethel Befekadu | |
| dc.contributor.author | Kemal Ahmed | |
| dc.date.accessioned | 2025-08-02T08:13:57Z | |
| dc.date.available | 2025-08-02T08:13:57Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Canine parvovirus (CPV-2) remains a leading and potentially fatal viral disease in canine populations, especially in young puppies. The presence of co-infecting pathogens can exacerbate disease severity and complicate clinical outcomes. This study aimed to detect CPV, characterize clinical signs, identify major bacterial co-infections, and assess treatment outcomes in puppies clinically suspected of CPV infection. A case-series study was conducted over eight months (October 2024 to May 2025) at AAU-CVMA, Professor Fisseha Gebreab Memorial Veterinary Teaching Hospital, Bishoftu, Ethiopia. Thirty fecal samples were purposively collected from diarrheic puppies suspected of CPV-2 infection. Samples were analyzed using microbiological methods and conventional PCR. All the examined puppies exhibited diarrhea, vomiting, and anorexia; 60% (18/30) showed bloody diarrhea. CPV was detected in 28 samples. Ten puppies tested positive for CPV alone, while co-infections with Salmonella or Escherichia coli were found in 16 cases, and two cases had both bacterial pathogens alongside CPV. One sample showed co-infection with Salmonella and E. coli without CPV, and one sample was negative for all tested pathogens. Following antibiotic and supportive treatment, five puppies died, while 25 recovered. The results demonstrate a high rate of CPV and frequent bacterial co-infections in diarrheic puppies, underscoring the complication of canine parvovirus infection with bacterial pathogens. This study highlights the need for further research on the prevalence and molecular characterization of CPV in the study area to improve diagnostic, treatment and prevention strategies | |
| dc.identifier.uri | https://etd.aau.edu.et/handle/123456789/5902 | |
| dc.language.iso | en_US | |
| dc.publisher | Addis Abeba University | |
| dc.subject | Canine parvovirus | |
| dc.subject | Clinical Signs | |
| dc.subject | Diarrhea | |
| dc.subject | E. coli | |
| dc.subject | Salmonella | |
| dc.subject | Puppies | |
| dc.title | “Clinical Characterization, Detection of Canine Parvovirus and Bacterial CoInfections, and Evaluation of Treatment Outcomes in Clinically Suspected Puppies at AAUCVMA Veterinary Teaching Hospital, Bishoftu, Ethiopia | |
| dc.type | Thesis |