Magnitude of common enteric bacteria and their Antimicrobial susceptibility pattern among governmental school children in a de-worming setting at Sululta, North Shewa, Oromia, Ethiopia.
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Date
2017-11
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Addis Ababa Universty
Abstract
Back ground: Current de-worming programs focus solely on reducing the morbidity caused by helminthes and often fail to monitor for indirect consequences of treatment on other pathogens. As human health reflects integrated impact of infectious agents to which hosts are exposed, it is crucial to monitor for unintended effects of mass drug treatments in co-infected populations.
Objective: To assess the magnitude of common enteric bacteria and their antimicrobial susceptibility patterns among governmental school children in a setting of mass de-worming Methods: A school based cross sectional study was conducted in three primary schools from April to June 2017 in Sululta, Oromia, Ethiopia. A structured questionnaire was used for data collection on socio-demographic characteristics of parents as well as for children. A total of 249 de-wormed and 88 non de-wormed school children were enrolled. Stool specimen was collected and cultured on primary isolation media and antimicrobial susceptibility patterns were done for bacteria with CLSI guideline. Data was entered and analyzed using SPSS version 21.
Results: Overall prevalence of enteric pathogen (intestinal parasite and bacterial) was 112(33.2%).From theses, 34(10.1%) were bacterial, 33(9.8%) were protozoa and 46(26.1%) were helminthes. 83 (33.3%) of the pathogens were from de-wormed group, of which 25(10%) were bacteria, 27(10.8%) protozoa and 31(12.4%) were of helminthes origins. The rest 29(32.9%) were detected from non de-wormed group which were 9(10.2%) bacteria, 5(6%) protozoa and 15(17%) helminthes). No statistically significant difference was noted between de-wormed and non-de-wormed groups with isolated bacteria. The dominant bacterial isolates were Salmonella spp. and E.coli O157 from pathogenic one and the least one was Shigella spp. All isolates showed 100% resistance to Ampicilin (10μg), but susceptible to nalidixic acid, Ciprofloxacin and cefteriaxone.
Conclusion: Overall prevalence of enteric bacteria was 34(10.1%) and magnitude of the common enteric pathogens among de-wormed and non de-wormed school children was relatively similar. Antibiotics like nalidixic acid, Ciprofloxacin and cefteriaxone are active against isolated pathogenic bacteria. Broad surveillance is needed to see the effect of mass de-worming and rational use of antibiotics should be encouraged.
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de-worming, school children, AST, Enteric bacteria, Oromia, Ethiopia