30 day’ Post-operative complicationsof Intracranial Meningioma Surgery
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Date
2020-01
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Addis Abeba University
Abstract
Background: Meningioma is the most common primary intracranial tumor. Even though
different management options exist in modern medicine, surgery is still the only cure for this
benign tumor. Surgical options are not without risk. Identifying and predicting the short-term
complications in an Ethiopian setup might be useful in the decision-making process before
surgery for our patients. This study uses a prospective design that aims to assess 30 days of posoperative complications of intracranial meningioma.
Methods: Aprospective study that was conducted at TASH, ZMH & MCM hospital between
November 1, 2019, and September 1, 2020. Assessment of postoperative complications was
determined in-person using a standard questionnaire in both inpatient & outpatient setup. For the
investigation, pathology & Intraoperative findings data were collected from medical charts,
radiology, and pathology archives.Data were checked for completeness and quality control aftewhich, it was entered on SPSS version 21 for analysis using logistic regression.
Results:A total of 77 patients were enrolled in the study. The mean age of the patients was
40.94 years. 71 (92%) patients presented with headache and 62 (80.5%) patients had one or
more focal neurologic deficits. Tumor was classified based on location and size. 47 (61%) of
the tumors were skull base tumors.The surgical mortality rate which was defined as death
within one month was 9.1%. Among all patients, 37 (48.1%)had one or more postoperative
complications of which new-onset or worsened focal deficit was the commonest. A significant
association was seen between skull base tumors and postoperative complications in both
bivariate and multivariate analyses witha p-value of 0.01 (OR=5.79, 95% CI: 2.061-16.312.
Conclusion: Even though the complications and mortality rates were high, surgery led to
symptom improvement in a large proportion of patients. Skull base meningioma, anesthesia
time more than 5 hours, and blood loss more than 1000ml hada significant association with
postoperative complications.
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Keywords
Post-operative complications,Intracranial Meningioma, Surgery