A two-yearretrospective review on theclinical and electrophysiologic profiles of Guillain-Barre Syndrome at two centers in Addis Ababa,Ethiopia

dc.contributor.advisorProf.Mengistu, Getahun(Internist, Neurologist &Headache specialist)
dc.contributor.advisorDr.Melka, Dereje(MD, Consultant Neurologist)
dc.contributor.advisorDr.Zenebe, Yared(MD, consultant Neurologist)
dc.contributor.advisorDr.Nuri, Hussien(MD, consultant Neurologist)
dc.contributor.advisorDr.Alemayehu, Samson (MD, consultant Neurologist)
dc.contributor.authorMulugeta, Abel
dc.date.accessioned2021-10-29T06:44:46Z
dc.date.accessioned2025-01-08T14:37:11Z
dc.date.available2021-10-29T06:44:46Z
dc.date.available2025-01-08T14:37:11Z
dc.date.issued2020-12
dc.description.abstractBackground: The clinical manifestations and electrophysiologic patterns of Guillain-Barre Syndrome(GBS)have been established with several studies previously.Nerve conduction study has been known to be one of the diagnostic tool complementing the clinical presentation of GBS patients. The aim of this study was to assess the clinical characteristicsand electrophysiologic pattern of GBSpatients at two facilities in Addis Ababa,Ethiopia. Methods:A retrospective cross-sectional study was conducted from October 1-30, 2020 upto by reviewing the medical record of GBS patientswho visited the neurology clinics at two facilities in Addis Ababa between from September 01, 2017 and September 30, 2019. Demographic, clinical, biochemical and electrophysiologic data were collected and analyzed. Results:A total of 59 GBS patients’ medical records were reviewed.Majority 46(72.8%)of the patients were male.The dominant age category was from 21-35 years of age having 26(44.1%)share.The mean age of the participants was 32.96 (15.04)years .Preceding illnesses were documented in 21patients wherediarrheal illness was reported by the majority (38%)followed by upper respiratory tract infections. Quadriparesis was the most frequent presenting symptom with 38(64.4%) patients. .Following the Nerve conduction test the two most common GBS variants identified were Acute Motor Axonal Neuropathy variant(AMAN)and AcuteInflammatory Demyelinating Polyneuropathy variants of GBS. Conclusion: The majority of GBS patientsincluded in our study were young adults who presented with quadriparesis, with the most common variant of GBS being AMAN variant.en_US
dc.identifier.urihttps://etd.aau.edu.et/handle/123456789/28393
dc.language.isoen_USen_US
dc.publisherAddis Abeba Universityen_US
dc.subjectGuillain-Barre Syndrome, Quadriparesis, variants of GBS,Nerve conduction studyen_US
dc.titleA two-yearretrospective review on theclinical and electrophysiologic profiles of Guillain-Barre Syndrome at two centers in Addis Ababa,Ethiopiaen_US
dc.typeThesisen_US

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