A Two-Yearretrospective Review on Theclinical and Electrophysiologic Profiles of Guillain-Barre Syndrome at two Centers in Addis Ababa,Ethiopia
No Thumbnail Available
Date
2020-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Addis Abeba University
Abstract
Background: The clinical manifestations and electrophysiologic patterns of Guillain-BarreSyndrome(GBS)have been established with several studies previously.Nerve conduction studyhas been known to be one of the diagnostic tool complementing the clinical presentation ofGBS patients. The aim of this study was to assess the clinical characteristicsandelectrophysiologic pattern of GBSpatients at two facilities in Addis Ababa,Ethiopia.
Methods:A retrospective cross-sectional study was conducted from October 1-30, 2020 upto byreviewing the medical record of GBS patientswho visited the neurology clinics at two facilitiesin Addis Ababa between from September 01, 2017 and September 30, 2019. Demographic,clinical, biochemical and electrophysiologic data were collected and analyzed.
Results:A total of 59 GBS patients’ medical records were reviewed.Majority 46(72.8%)of thepatients were male.The dominant age category was from 21-35 years of age having 26(44.1%)share.The mean age of the participants was 32.96 (15.04)years .Preceding illnesses weredocumented in 21patients wherediarrheal illness was reported by the majority (38%)followed byupper respiratory tract infections. Quadriparesis was the most frequent presenting symptom with38(64.4%) patients. .Following the Nerve conduction test the two most common GBS variantsidentified were Acute Motor Axonal Neuropathy variant(AMAN)and AcuteInflammatoryDemyelinating Polyneuropathy variants of GBS
Conclusion: The majority of GBS patientsincluded in our study were young adults whopresented with quadriparesis, with the most common variant of GBS being AMAN variant.
Description
Keywords
Guillain-Barre Syndrome, Quadriparesis, variants of GBS,Nerve conduction study