Magnitude and Antimicrobial Resistance Pattern of Staphylococcus aureus among Mother Child pairs isolated from nasal swab at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
| dc.contributor.advisor | Desta, Kassu(MSc, PhD candidate, Associate Professor) | |
| dc.contributor.author | Abtew, Mekedlawit | |
| dc.date.accessioned | 2020-05-21T17:57:18Z | |
| dc.date.accessioned | 2023-11-06T08:56:32Z | |
| dc.date.available | 2020-05-21T17:57:18Z | |
| dc.date.available | 2023-11-06T08:56:32Z | |
| dc.date.issued | 2019-06 | |
| dc.description.abstract | Background: Staphylococcus aureus is a leading cause of hospital acquired infections. It’s the primary cause of lower respiratory tract infections, surgical site infections, second leading cause of nosocomial bacteremia and cardiovascular infection. Methicillin-Resistant Staphylococcus aureus infections in the pediatric population are associated with significant morbidity and hospital costs. Mode of transmission from mother to child by shortly after birth and can become colonized quickly after contact with adult skin or their environment. Objectives: To determine the Magnitude and antimicrobial resistance pattern of Staphylococcus aureus among mother child pair from nasal swab at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods: A cross-sectional study were conducted from March to July 2018 among pediatric emergency outpatients and expanded program on Immunization aged under five in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Nasal swab were collected using sterilized cotton swab from each child and mother. Standard techniques of culture on both blood agar and Mannitol Salt agar were used for isolation and identification of S. aureus along with catalase and coagulase test .Antimicrobial susceptibility test was performed using a disk diffusion method on Muller Hinton agar. The data were analyzed by stastical package for the social sciences package software version 20.0 and Microsoft excel. Results: From total of 212 mother child pair 25(11.8%) child and 31(14.6) mothers had Staphylococcus aureus in their nasal cavity. The mean age of pediatrics participants in this study was 2.0047 ± 0.58 (SD standard deviation) years. Two Methicillin-Resistant Staphylococcus aureus isolates was detected from mothers in pediatrics EOPD 2(3.6%). About 89.3% of Staphylococcus aureus was resistance to Penicillin and 17.9% which were also resistance to Gentamicin (Tobramycin). Conclusion: This study showed lower rate of nasal carriage of mother child pair of S.aureus and Methicillin-Resistant Staphylococcus aureus. Therefore developing decolonization protocols and proper utilization of drugs are needed to reduce the transmission of S.aureus and the burden of Methicillin-Resistant Staphylococcus aureus. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/21280 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | MRSA, Mother Child pair, AST, TASH | en_US |
| dc.title | Magnitude and Antimicrobial Resistance Pattern of Staphylococcus aureus among Mother Child pairs isolated from nasal swab at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. | en_US |
| dc.type | Thesis | en_US |