Trends in Inpatient Admissions and The Magnitude of Early Mortality Among Pediatric Haemato-Lymphoid Cancer Patients At Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia

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Date

2025-10-13

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Addis Ababa University

Abstract

Background Cancer is a major cause of childhood morbidity and mortality worldwide. Each year, nearly 273,000 children and adolescents under the age of 20 are diagnosed with cancer. While the overall survival rate for children with cancer has reached 80% in many high income countries (HICs), in lower-middle-income countries (LMICs) and low-income countries (LICs), figures are significantly lower with rates falling below 30%. Globally, leukemia is the most common childhood cancer, followed by brain tumors and lymphomas, though the distribution varies geographically. Early mortality (EM), defined as death within the first 42 days of diagnosis or admission. Early mortality reflects limitations in timely diagnosis, supportive care, infection management, and treatment access. Objective: To asses Early Death (ED) at TASH, Pediatric Hematology and Oncology Unit And to analyze the types and causes of mortalities across different Cancer types Method: A facility-based Cross-sectional study will be conducted on All children with newly diagnosed childhood cancer who admitted at the TASH PHOC unit. Data will be collected from charts. Data will be entered into Statistical Package for Social Sciences version 25 (SPSS) for subsequent descriptive and analytical statistics where applicable. Statistically significant association will be taken for p value of <0.05. Budget and Work plan: The study will be conducted from 1 January, 2023 to 31 January, 2025.G.C with estimated total cost of 36,825 Birr, the cost will be sponsored by Addis Ababa University, College of health science.

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Keywords

Childhood cancer, Pediatric hemato-lymphoid malignancies, Early mortality, Inpatient admissions, Leukemia, Lymphoma, Sepsis, Diagnostic delay, Tikur Anbessa Specialized Hospital (TASH), Ethiopia.

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