Oral Newcastle Disease Vaccination Trials and Studies of Newcastle disease In Ethiopia
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Date
1998-01
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AAU
Abstract
Oral Newcastle Disease Vaccination Trials and Studies of Newcastle disease In Ethiopia ==Three laboratory trials Wert: conducted in commercial broiler chickenst to determine efficacy of the heat-resistant NDV-12 vaccine (similar to V4 vaccine). and to compare the NDV-I~ vaccine with conventional vaccines (HBI and LaSola). Sorghum and barley were tested for their suilabiJity as vaccine carriers for oral administration. Further one eight field isolates of NOV were tested for their pathogenicity and nine ND outbreaks between 1983 and 1995 in state poultry farms in Ethiopia were studied retrospectively. In the vaccination Trials, chickens were vaccinntcd twice or three timcs with NDV-i2 and conventional vaccines via the ocular and/or the drinking water route, and via feed with parboiled and untreated barley and sorghum as carriers. Sera were collected al wekly intervals up 10 the end of the triias and were tested for haenugglutinatioll.inhibition (Hi) activity. The protcection level was assesse'-lebratu d by challenging the chickens intramuscularly by a locatly isolated velogenic strain of NDV