Four years retrospective study on clinical characteristics, risk factors and outcomes of patients with pulmonary embolism admitted in Tikur Anbessa Specialized hospital medical ward
| dc.contributor.advisor | Dr. Yusuf, Hanansuf (MD, Internist, Consultant PCCM physician) | |
| dc.contributor.author | Amanu, Esubalew | |
| dc.date.accessioned | 2021-02-28T06:52:46Z | |
| dc.date.accessioned | 2023-11-05T09:37:03Z | |
| dc.date.available | 2021-02-28T06:52:46Z | |
| dc.date.available | 2023-11-05T09:37:03Z | |
| dc.date.issued | 2021-01 | |
| dc.description.abstract | Background Pulmonary embolism is the third common cardiovascular problem globally. It is a potentially lethal condition and frequently underdiagnosed. The severity and clinical presentation of PE are variable. Hence, correct diagnosis is dif cult. Prompt diagnosis of PE is essential to reduce mortality. Most of the data on the natural history, risk factors and clinical outcomes of PE comes from the Western population and there is lack of data in Africa and in Ethiopia specifically. This study assessed the clinical characteristics, risk factors and outcomes of PE patients in Tikur Anbessa Specialized Hospital, Ethiopia to fill the information gap we have. Objective- to assess the clinical characteristics, risk factors and outcomes of PE patients admitted in TASH medical ward from December 2016 G.C.to July 2020 G.C. Methods- A hospital based retrospective study was done in 60 patients who were admitted in TASH medical ward from December 2016 G.C.to July 2020 G.C. with the main diagnosis of PE confirmed by chest CT with contrast and CTPA. All patients who had complete data wereincluded in the study and their medical charts were reviewed. Data were analysed using SPSS 26 and descriptive analysis was used. Results- A total of 60 patients studied. Of those 56.7% are females. The median age of patients was 44.6 years. Majority (95%) of the patients were symptomatic and the most common presenting symptoms were; shortness of breath, cough, chest pain, leg swelling and hemoptysis accounting 75%, 50%, 41.7%, 33.3% and 13.3 % each respectively. At presentation 95% were tachypenic, 76.7% tachycardic and 11.7% were hemodynamically unstable. 80% of the studied patients had one or more risk factors for PE. From those risk factors; active cancer, major surgery, peri and post-partum period and immobilization all together accounts the majority (83.3%). 6(10%) patients died in medical ward, 16.7% transferred to medical ICU and 73.3% were discharged improved. Conclusions and Recommendations- More than half of PE patients were females and 60% were younger than 45 years old. 95% of patients were symptomatic. Majority of the patients admitted had one or more risk factors. Active cancer, major surgeries, peri and post-partum and immobilization constituent the most common risk factors. The coverage of thromboprophylaxis should be increased focusing on patients who have the above risk factors. And further study should be done which shows the effect of those risk factors on patients’ outcomes. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/25256 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | Pulmonary embolism, clinical characteristics, risk factors, outcome, Tikur Anbessa Specialised Hospital, Ethiopia | en_US |
| dc.title | Four years retrospective study on clinical characteristics, risk factors and outcomes of patients with pulmonary embolism admitted in Tikur Anbessa Specialized hospital medical ward | en_US |
| dc.type | Thesis | en_US |