Bioactive metabolites from the cultures of Phellinus sp. and Lentinus velutinus
| dc.contributor.advisor | Dagne Ermias (PhD) | |
| dc.contributor.author | Lemma Bekele | |
| dc.date.accessioned | 2018-06-14T12:14:18Z | |
| dc.date.accessioned | 2023-11-09T16:19:50Z | |
| dc.date.available | 2018-06-14T12:14:18Z | |
| dc.date.available | 2023-11-09T16:19:50Z | |
| dc.date.issued | 1994-06 | |
| dc.description.abstract | The ethyl acetate extract of the fermentation culture broth of Phellinus sp. gave two i compounds identified as3-chloro-4-methoxybenzaldehydeand 3,4-dimethoxybenzaldehyde. I Both 3-chloro-4-methoxybenzaldehyde and 3,4-dimethoxybenzaldehydeshowed phytotoxic j i activity and lethality to brine shrimp ( Artemia salina Leach) but 3,4- ji dimethoxybenzaldehyde showed weaker activity. Both 3-chloro-4-methoxybenzaldehyde and 3,4-dimethoxybenzaldehyde were isolated for the first time from the genus Phellinus. The structures were elucidated by spectral analyses and synthesis. A fatty acid and a triglyceride were also isolated from the Phellinus sp. grown on rice. ! The ethyl acetate extract of the fermentation culture broth of Lentinus velutinus gave rise i to three compounds of which two were identified as the antibiotic compounds hypnophilin J and velutinol and the third as the antitumour compound panepoxydon. Velutinol was j reported earlier from the culture filtrate of the same fungus, however, hypnophilin and panepoxydon have not hitherto been reported from the genus Lentinus. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/12345678/941 | |
| dc.language.iso | en | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | Fermentation culture broth of Phellinus sp. | en_US |
| dc.title | Bioactive metabolites from the cultures of Phellinus sp. and Lentinus velutinus | en_US |
| dc.type | Thesis | en_US |