Study on Mycobacterium Bovis Infection in Umans and Animials in North West Shoa Zone, Oromia National Regional State

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Date

2005-06

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AAU

Abstract

A case control study was conducted between October 2005 and April 2005 to assess the My cobactium bovis and other Mycobacterium complex infection In callie and Their respective owners in selected districts of North Shoa Zone of Oromia National Regional State. Central Elhiopa. A total of 174 cattle owners (87 tuberculosis cases and 87 controls). And 1041 heads ofeanlc (506 owned by cases while 535 owned by controls) were included In the Study. The methods used were comparative interademlal cervcal tuberculin test (CIDT). Mycobacteriology. Acid fast staining. Chest x-ray, biochemical tests and drug suscepllbility Test. The prevalence of tuberculosis was significantly (x2=48.4, P<0.001) higher In cattle Owned by tuberculosis p atjems (24.3%) than in cattle owned by controls (8.6%), and thus. Cattle owned by a tuberculosis patient was about four times more hkeily to be infected (Odds Ratio. OR=4.2 ,95% CI= 2.79.6.2)with tuberculosis than cattle owned by a tuberculosis free Owvner. Funher. Cattle owners who consumed raw milk were at higher risk (x2=14.12, P<0.001,OR=3.34)Of acquiring tuberculosis than those who consumed boiled milk. The Prevalence of Tuberculosis in canle was significantly higher in exotic breeds( x2=101.3, P<0.05,OR =74) Animals older than 4 years (x2=39.2, P<0.001, OR = 5), and animals in poor physical condition (x2-15.3, P<0.003, OR = 2.S). Of the 42 human isolates, 31(73.8%) were ,Mycobaclerlunt Tuberculosis. 7 (16.28%) were Mycobacterium bovis while 4 (9.S%) \were atypical Mycobacteria as demonstrated by biochemical and drug se nsitivity tests. On the other band. Of The II cattle Isolates, 2 (18.1%) were M. Tuberculosis. 5 (45.5%)M bovis and 4(36A%) were Atypical mycobacteria. In conclusion. The results of the present study showed the transm ission Of mycobacterial species between cattle and their Owners.

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Keywords

Infection in umans

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