The Prevalence and Predictive Factors of Recurrent Deep Venous Thrombosis in Addis Ababa University Black Lion Hospital Emergency Department from April1, 2017-April1, 2020G.c.
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Date
2020-10
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Addis Abeba University
Abstract
BACKGROUND: About 2-5% of people experience deep-vein thrombosis (DVT) during their
lives. Death, disease recurrence, post-thrombotic syndrome, and excessive bleeding due to
coagulant medications are among the most important DVT complications. Recent research found
a high incidence of DVT recurrence after the first attack. Disease recurrence has a multifactorial
pathogenesis and its probability is related with the number and severity of risk factors. The
present study aimed to investigate DVT recurrence and the associated risk factors.
Method This retrospective cross-sectional study evaluated all DVT patients hospitalized in
Tekur Anbessa hospital emergency department during April 2009 to April 2012. The risk factors
were obtained from patients' records including smoking, intravenous drug abuse, coagulopathy
disorder having a history of surgery, history of cardiac disease, cancer, immobilization and
trauma. A standardized structured questioner composed of closed-ended questions was used to
collect the data and it was adopted from a study Marianne Tang Severinsen on their PhD thesis.
The questionnaire is compose of closed ended question, mostly composed of tables and some yes
and no question.
Results A total number of 532 DVT patients were hospitalized in Taker Anbesa Hospital
Emergency department during the study period. It was only possible to extract the data from 130
patient records. A history of recurrent DVT was reported in 30 individuals (23%). The
comparison between the risk factors in patients with a first time DVT and those experiencing a
recurrent DVT revealed significant differences solely in the prevalence of blood disorders.
Applying stepwise regression indicated coagulopathy (OR: 5.389; 95% CI: 0.004-0.761; P <
0.048) with DVT recurrence
Conclusion Based on our findings, DVT patients with blood disorder have high risk of
recurrence, so that it should be recommended to have through investigation and management of
coagulopathy disorders.
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Keywords
Venous thrombosis