Serum Immunoglobulin Levels in Healthy Ethiopian School Childhen
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Date
1982-06
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Addis Ababa University
Abstract
Serum concentrations of immunoglobulins IgG, IgA and IgM in
258 healthy Ethiopian school children and 82 healthy adults rosiding
in Addis Abeba were measured by the radial immunodiffusion
technique. The results are presented as geometric mean values
in mg/100 ml and as percent of the adult mean values. A Btatistical
analysis showed that the IgG and IgA concentrations at
ages 8 and 7 respectively were lower than the adult values. The
inference drawn ftom these results is that the IgG and IgA levels
do not reach the adult level until after the age of 8 and 7
respectively. In contrast the IgM level was found to reach the
adult level before the age of 7. No truly significant differences
were observed in immunoglobulin levels which could be attributed
to sex, intestinal parasitic infection or socio-economic status.
The merul values for IgG and IgM obtained from this Btudy were
found to be higher than the reference values being uBed in the
country at the mo-ment. It is thuB suggested that mean immunoglobulin
concentration values obtained from this study be used
as reference values until further study is made and more refined
reference values are set.
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Biology