Hematological Profile of Pregnant Women Attending Antenatal Care at Dilla University Referral Hospital, Dilla, Ethiopia: Comparative Cross Sectional Study
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Date
2016-10
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Addis Ababa University
Abstract
Background: Pregnancy manifests number of change in the normal physiology. Important of
these changes are those which alter the hematological parameters. Hematological profile is
considered one of the factors affecting pregnancy and its outcome. Anemia is the most common
hematological problem in pregnancy.
Objective: To assess the hematological profile of pregnant women in comparison with non
pregnant women (as a control).
Methodology: Comparative cross sectional study was conducted from March to May, 2016, on
110 pregnant and 110 non pregnant women at Dilla University Referral Hospital. A structured,
pretested and interviewer administered questionnaire and laboratory tests were used to obtain
data. Data was analyzed using the statistical soft ware SPSS version 20. Logistic regression,
independent t test and one way ANOVA was used. P value less than 0.05 were taken as
statistical significant.
Result: The result showed that pregnant women exhibited statistically significant decrease value
of RBC, Hb, HCT, MCHC, Lymphocyte, MID and PLT counts when compared with non
pregnant. White blood cell, neutrophils and MCH were significantly higher in pregnant women
compared to non pregnant women. No significant difference in MCV and RDW of pregnant
women compared to non pregnant women. There was a significant decrease in RBC, Hb and
HCT in the 2nd trimester compared to 1st trimester pregnancy. The RDW value increased
significantly in third trimester when compared with 1st trimester pregnancy. The prevalence of
anemia obtained in this study was 15.5%. Pregnant women who had primary educational level
were 6.28 times more likely to be anemic compared to higher educational level.
Conclusion: There was a significant difference in the majority of hematological parameters
between pregnant and non pregnant women. RBC, Hb, HCT, MCHC, Lymphocyte, MID and
platelet counts were significantly decreased whereas WBC, neutrophils and MCH were
significantly increased in pregnant women.
Therefore, there is a need to monitor these
parameters during pregnancy and thus improve the outcome of pregnancy.
Key terms: Hematological profile, pregnant women, anemia
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Keywords
Hematological profile, pregnant women, Anemia