Bacterial and Fungal Infection and their Drug Susceptibility Pattern in Burn Patients Admitted to Yekatit 12 Hospital Medical College and AABET Hospitals
| dc.contributor.advisor | Dr.Bitew, Adane(MSc, Ph.D.) | |
| dc.contributor.advisor | W/Senbet, Zerihun | |
| dc.contributor.author | Garedew, Andualem | |
| dc.date.accessioned | 2021-11-29T06:16:39Z | |
| dc.date.accessioned | 2023-11-06T08:57:09Z | |
| dc.date.available | 2021-11-29T06:16:39Z | |
| dc.date.available | 2023-11-06T08:57:09Z | |
| dc.date.issued | 2021-06 | |
| dc.description.abstract | Background: Managing the burn wound is necessary to heal the wound early but the infected one not only needs appropriate management of burn therapy, in addition to that, doing culture for the potential bacteria and their antimicrobial susceptibility pattern necessary. Furthermore Large wound surface, impaired immune systems, and broad-spectrum antibiotic therapy contribute to the growth of opportunistic fungal species. Mycosis in burns is likely to be underestimated. Objectives: To determine the magnitude of bacterial and fungal infections and their antimicrobial susceptibility pattern of burn patients at Yekatit12 and AABET Hospital, Addis Ababa, 2021. Methods: A cross-sectional study was conducted in Y12HMC and AABET hospital from January to June 2021. Burn Wound swab specimen was collected using sterile cotton swab and processed and analyzed for bacteriological and fungal culture medias like Potato dexterous agar, Chrome agar, Blood agar, MacConkey agar, Biochemical test and AST. The data was analyzed using SPSS version 25. Results: 240 burn patients were included in the study a total of 154(64.2%) bacterial pathogens were recovered. Among the isolated 154 (64.2%) bacteria 110 (71.4 %) were gram-positive and 44 (28.5 %) gram-negative bacteria. From gram-positive bacteria, predominant bacteria isolates were CoNs 55 (22.9 %), followed by S.aureus 54 (22.5%) while gram Negative bacteria isolated the most predominant bacteria were Pseudomonas aeruginosa 17(7.1%)from 66 (27.5%). Fungus isolation 38 (57.5%) were yeast and 28 (42.2 %) mold .The susceptibility patterns of isolates 60% of resistance to the antibiotics tested. Klebsiella species demonstrated high level of resistance to Ampicilin and ceftazidime each 5(100%), Tobramycin, ciprofloxacin and gentamicin each 3(60%). Amikacin was relatively effective against 23(95.8%) of the Klebsiella species. CONCULUSION: The wounds were contaminated with various types of bacteria. This might be a reflection of inappropriate use of antibiotics. The presence of MDR in the wound may be a factor for persisted infection. Some of the participants in the study area had a positive fungal result. It is not contemptible it an alarming finding that needs more focus and follow-up on the fungal infection. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/29005 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Abeba University | en_US |
| dc.subject | Multidrug resistance, antimicrobial susceptibility pattern. | en_US |
| dc.title | Bacterial and Fungal Infection and their Drug Susceptibility Pattern in Burn Patients Admitted to Yekatit 12 Hospital Medical College and AABET Hospitals | en_US |
| dc.type | Thesis | en_US |