Pregnancy outcome For Rh-D Alloimmunized Pregnancies at Two Teaching Hospitals (Tash And Gmh), Addis Ababa, Ethiopia, 2023
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Date
2023-10
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Addis Ababa University
Abstract
Rh alloimmunization refers to the process by which antibodies are produced
against the Rh antigens that are found on the surface of red blood cells (RBCs). The disease
burden is worse in developing countries, where universal anti D prophylaxis for Rh negative
mothers is very suboptimal. The annual burden of still birth, neonatal death & severe
hyperbilirubinemia is projected to be 41,000, 90,000, and 97,000 respectively. In a recent study
at the three teaching hospitals of AAU the prevalence of Rh Alloimmunization is found to be
17.1%. This study provides measured pregnancy outcome for those mothers who are
alloimmunized with Rh D antigen.
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Keywords
RH-D alloimmunization, intrauterine transfusion, hydrops