Magnitude of Hepatitis B, Hepatitis C, Syphilis and their Associated Factors among Emigrants come for Medical Checkup in Labco Advanced Clinical Laboratory, Addis Ababa, Ethiopia.
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Date
2021-10
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Addis Abeba University
Abstract
Background: Viral Hepatitis is a contagious liver disease mainly caused by hepatitis B virus and
hepatitis C virus. Syphilis is an infectious venereal disease caused by the spiral-shaped bacterium
Treponema palladium. Globally, Hepatitis B Hepatitis C and syphilis are common conditions
associated with high morbidity and mortality.
Objective: To assess the magnitude of Hepatitis B, Hepatitis C, Syphilis and Their Associated
Factors among Emigrants come for medical checkup in Labco Advanced Clinical Laboratory,
Addis Ababa, Ethiopia.
Methods: A cross-sectional study was conducted among 500 emigrants, from February until
April 2021. A questionnaire was used to collect emigrants ’socio-demographic and risk factors,
of hepatitis B, hepatitis C and syphilis infections. Five milliliters of blood sample were collected
from each participant and the serum was used for HBsAg, anti-HCV antibody and Syphilis
screening rapid tests. Reactive samples were further tested and confirmed by ELISA method.
Data was analyzed using SPSS version 26 software package. To identify associated factors,
Bivariable and Multivariable binary logistic regression analyses were done. Statistical
significance was considered at level of significance of 5%, and adjusted odds ratio (AOR) with
95% confidence interval (CI) was used to present the estimates of the strength of the association.
Result: In this study, a total of 500 emigrants were participated making a response rate of
96.8%. Among the total participants, 36.4% (n=182/500) were male and 63.6 % (n=318/500)
were female resulting in a male-to-female ratio of 1:2. The overall magnitude of Hepatitis B,
Hepatitis C, and Syphilis were 2.2%, 0.2%, and 0.6% respectively. The identified independent
determinants of HBsAg were exchange of sharp materials and history of tooth extraction with
[AOR= 7.89; 95% CI 1.75-34.95:].and [AOR= 24.92:95% CI (5.95-104.4):], respectively.
Conclusion: The magnitude of HBsAg was intimidate, anti-HCV and syphilis was low among
Emigrants attending in Labco Advanced Clinical Laboratory according to WHO criteria.
Exchange of sharp materials and history of tooth extraction are independent determinants of
HBsAg.
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Keywords
Hepatitis B, Hepatitis C, Syphilis, Emigrants, Addis Ababa, Ethiopia.