Effect of Priming Principle on the Induction Dose Requirement of Propofol, and its Effect on Hemodynamic Parameter and Pain at Injection Site in Patient Undergoing Electives Surgeries Under General Anesthesia Public Hospital Addis Ababa Ethiopia from February 1 to April 30, 2022/2023,a Prospective Cohort Study
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Date
2023-06-09
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Addis Ababa University
Abstract
Priming techniques often referred to as auto co-induction is the procedure of delivering a pre-calculated amount of an induction agent prior to administering the full dose of the same agent. The process of inducing of anesthesia is regarded as among the greatest significant instances in the administration of IV agent because it has been linked with a wide range of hemodynamic variations. Several induction agents have been used to induce anesthesia, with propofol gaining popularity due to its pharmacokinetic profile, but its primary drawback was its wide hemodynamic variability, which was mostly dose dependent. In order to preserve the hemodynamic balance during propofol induction, different strategies were used. including concurrent use of N2O, administration of opioids, administration of sedative, and the use of benzodiazepines such as Midazolam, the addition of local anesthetics or magnesium sulphate, and the application of the priming principle).
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the Induction Dose Requirement of Propofol, And Its Effect on Hemodynamic Parameter