Magnitude of Delirium and Associated Factors at Intensive Care Units of Selected Governmental Hospitals in Addis Ababa, Ethiopia from September 2022 to November 2022
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Date
2023-04-19
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Addis Ababa University
Abstract
Delirium is defined as mental disorder of acute onset and fluctuating course characterized by disturbances in consciousness, orientation, memory, thought, perception, and behavior and its incidence is nearly 50% in ICU in those non intubated patients whereas in intubated patients it rises approximately to 80% according to different studies. Furthermore, ICU delirium is associated with negative outcomes such increases length of ICU stay, prolonged mechanical ventilation, a high rate of admission after discharge and over all increased patient mortality according to varieties of studies.
Objectives: The objective of this study is to assess the magnitude of delirium and associated factors in intensive care units of selected governmental hospitals in Addis Ababa, Ethiopia.
Methods: Institution based multicenter cross-sectional study was conducted on patients admitted to intensive care units of selected governmental hospitals in Addis Ababa from September1, 2022 to November 30, 2022.Froma total of 403patientsselected from Four hospital using simple random sampling technique 388 Patients were included in the final analysis. Before being imported into STATA/MP version 17, the data were originally input into Epidata version 4.6. The analysis fitted bivariable and multivariable binary logistic models to find the explanatory variables. The 95% confidence interval of the odds ratio (OR) was calculated, and factors with a p-value less than 0.05 in the multivariable model were declared significantly associated with the dependent variable.
Results: incidence of delirium in the ICU at selected Addis Ababa hospitals was 31.44% (95% CI: 27.00%, 36.25%).age(AOR= 5.29, 95%CI: 2.28, 12.84), coexisting illness (AOR= 4.23, 95%CI: 1.97, 9.78), alcohol history (AOR= 6.72, 95%CI: 2.68, 20.48), and APACHE II score (AOR= 1.11 95% CI: 1.05, 1.17) were significantly associated with delirium in ICU.
Conclusion: Delirium was high at Four Addis Ababa government hospitals' ICUs. Age, concurrent disease, alcohol history, and APACHE II score were significant ICU delirium predictors.
Keywords: intensive care unit, Delirium, CAM-ICU, ICDSC, APACHE score
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Keywords
intensive care unit, Delirium, CAM-ICU, ICDSC, APACHE score