Treatment outcome and associated factors in acute heart failure patients at Tikur Anbessa Specialized Hospital, Ethiopia
| dc.contributor.advisor | Nedi, Teshome (PhD) | |
| dc.contributor.author | Tirfe, Mulubirhan | |
| dc.date.accessioned | 2018-11-27T09:13:47Z | |
| dc.date.accessioned | 2023-11-29T04:30:30Z | |
| dc.date.available | 2018-11-27T09:13:47Z | |
| dc.date.available | 2023-11-29T04:30:30Z | |
| dc.date.issued | 2018-02 | |
| dc.description.abstract | Treatment outcome and associated factors in acute heart failure patients at Tikur Anbessa Specialized Hospital, Ethiopia Mulubirhan Tirfe Tesfay Addis Ababa, Ethiopia February 2018 Heart failure is a syndrome when the heart fails to pump blood at a rate commensurate with the requirements of the body. Acute heart failure is a recent worsening of sign and symptom of heart failure requiring emergency visit and hospitalization. The aim of this study was to evaluate treatment outcome and associated factors that predict poor treatment outcome in acute heart failure patients at emergency department and medical ward. A prospective observational study was designed to evaluate predictors of poor treatment outcome. Data was reported as mean ± SD for continuous variables with normal distributed and median (interquartile range) with non-normal distributed variables; and chi square test was used for categorical variables. Bivariate and multivariate logistic regression analysis was used to evaluate factors that predict poor treatment outcome; p-value ≤ 0.05 was considered statistically significant and reported as 95% CI. Statistical package for social science (SPSS version 20) was used to enter and analyze data. The median age of patients with acute heart failure was 34 years (IQR = 23 to 50) and median hospital stay was four days (IQR = 3 to 6) with female (54.4%) dominance. The leading precipitating factor and underlying disease found at admission were pneumonia (47.5%) and chronic rheumatic heart disease (48.5%), respectively. Out of the 169 patients, 17.2% had poor treatment outcome among these six (3.6%) patients died. In multivariate logistic regression analysis smoking (adjusted odds ratio [AOR] = 8.7, p = 0.006), diabetes mellitus (AOR = 10.2, p = 0.005), pulmonary hypertension (AOR = 4.3, p = 0.016) and presence of adverse drug events (AOR = 4.2, p = 0.003) were predictors of poor treatment outcome. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/14556 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa Universty | en_US |
| dc.subject | acute heart failure; predictor; treatment outcome | en_US |
| dc.title | Treatment outcome and associated factors in acute heart failure patients at Tikur Anbessa Specialized Hospital, Ethiopia | en_US |
| dc.type | Thesis | en_US |