Incidence and Risk Factors of Post Extubation Laryngeal Edema Among Intubated Patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia in 2023. a Cross Sectional Study

Yifru Tadesse

Incidence and Risk Factors of Post Extubation Laryngeal Edema Among Intubated Patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia in 2023. a Cross Sectional Study

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Yifru Tadesse.pdf (1.01 MB)

Date

2023-06-06

Authors

Yifru Tadesse

Publisher

Addis Ababa University

Abstract

Post extubation laryngeal edema is the prominent complications of endotracheal intubation that require immediate diagnosis and intervention. It is the leading cause of airway obstruction that requires re-intubation. In spite of these there is no adequate information related to the exact incidence of post extubation laryngeal edema among studies. Objective: To determine the incidence and risk factors of post-extubation laryngeal edema among intubated patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Method: A cross sectional study was conducted at TASH from January 1, to March 30, 2023 by using well-structured questionnaires. Data entry was performed by Epi- info version 7.2.5 and the analysis was carried out by SPSS version 25.A descriptive statistics, bivariate and multivariate analysis was performed in which incidence and risk factors of post extubation laryngeal edema were determined at P-value < 0.05 and 95% CI. Results: Out of 193 patients enrolled 31[16.1%; 95% CI; 12.1, 20%] had developed post extubation laryngeal edema. Increased duration of intubation (AOR=18.385;95%CI; 2.823, 119.743; PV=0.002),Increased number of attempt during intubation (AOR=17.921; 95% CI; 2.823, 134.342; PV=0.005),Age < 17 years(AOR=50.383; 95%; 5.966,425.492;PV < 0.0001) ,Age between 17- 65 years (AOR=5.585; 95% CI; 1.399,22.296; PV=0.015) were significant risk factors to develop post extubation laryngeal edema. Conclusions: The overall incidence of post extubation laryngeal edema was 16.1%.Increased duration of intubation, increased number of attempt, and age of the patients were identified as significant risk factors to develop post extubation laryngeal edema. For these reason, clinicians and Tikur Anbessa Specialized Hospital should implement safest management strategies that significantly reduce the risks of post extubation laryngeal edema.