Hesitancy in Human Papilloma Virus Vaccine Uptake and its Associated Factors among Female Students in Jimma Town, Oromia, Ethiopia
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Date
2023-10-09
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Addis Ababa university
Abstract
Background: The human papillomavirus (HPV) vaccination strengthens the body's defenses against the viral strains that cause cervical cancer. It has contributed to a reduction in cervical cancer-related morbidity and mortality, which is one of the great public-health success stories. Despite the fact that vaccination reluctance is one of the world's top ten health challenges, there is a shortage of evidence in Ethiopia to completely understand vaccination-related hesitancy behavior. The primary objective of this thesis was to assess hesitancy of HPV vaccine uptake and associated factors among female students, in Jimma Town, Oromia, Ethiopia.
Methods: An institution-based cross-sectional study was conducted on 373 respondents, using both quantitative and qualitative approaches. The Data were collected by using pretested interviewer administered structured questionnaire, and in-depth interview. Logistic regression model was utilized to find independent predictors of female students’ hesitation to receive the HPV vaccine. The threshold for statistical significance was set at p-value < 0.05 for all variables. Qualitative data were done by describing parents' perceptions about HPV vaccines until reached the saturation level.
Details from an in depth interview were recorded, then transcribed verbatim, coded, organized by themes, and evaluated thematically. Findings were corroborated at interpretation.
Result: The hesitancy of the HPV vaccine in Jimma Town female students were 39.02% 95% CI (34.1, 44.1). Female school students who have smart phone, (AOR=0.51, 95% CI(0.28,0.94), mothers educational status (>= Secondary) (AOR=0.53, 95% CI(1.11,2.44), older sister vaccinated (AOR=0.04, 95% CI(0.004,0.42), previously vaccinated of HPV (AOR=0.64, 95% CI(0.006,0.137), distrust in safety & efficacy of vaccine (AOR=3.21, 95% CI(1.42,13.45) , think of unnecessary to receive HPV vaccinations (AOR=2.37, 95% CI(1.20,4.67), believe in learning stress not prevent from vaccinated (AOR=0.36, 95% CI(0.16,0.81), and Not Belief in rumors (HPV vaccine ruins girls fertility) (AOR=0.21, 95% CI(0.34,0.96), were found to be statistically significant with HPV Vaccine Hesitancy. Among the key causes showed by qualitative findings were poor perception, mistrust of vaccine safety and efficacy, fear of side effects, a lack of proper information, and misinformation.
Conclusion: The study found that HPV vaccine hesitancy is influenced by factors such as smartphone ownership, education, vaccination history, learning stress, and belief in vaccine rumors. However, hesitancy is also linked to concerns about vaccine efficacy and safety, suggesting the need for increased vaccination uptake.
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Keywords
Human papillomavirus; Vaccination; Hesitancy