Determinants of Chronic Respiratory Symptoms among Pharmaceutical Factory Workers in Addis Ababa Ethiopia
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Date
2017-06
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Addis Abeba Universty
Abstract
Background:-Chronic respiratory symptoms including chronic cough, chronic phlegm, wheezing, shortness of breath, and chest pain are manifestations of respiratory problems which are mainly evolved as the result of occupational exposures. Workers engaged in manufacturing, research and development of pharmaceuticals are potentially exposed to drug substances and also to chemical precursors that are potentially hazardous to health.
Objective:-To assess determinants of chronic respiratory symptoms among pharmaceutical factory workers.
Methods: -A case control study was done among 453 pharmaceutical factory workers with 151 cases and 302 controls. Cases were workers who had chronic respiratory symptom/s within one year period in the pharmaceutical factories from February 2016 to February 2017. Controls were workers who had no any chronic respiratory symptom/s within one year period in the pharmaceutical factories from February 2016 to February 2017. Prior to the actual data collection, a base line survey was conducted for one week to identify source of cases and the controls from each site. Study subjects were selected using simple random sampling technique. Data was collected using pretested and structured questionnaire by trained data collectors. Descriptive statistics, bivariate logistic and multivariate logistic regression analysis was done to see association between determinant factors and chronic respiratory symptoms.
Result: Workers’ Previous history of chronic respiratory diseases (AOR 3.36, 95%CI (1.85 - 6.12)), family history of chronic respiratory diseases (AOR=2.55, 95% CI, (1.51 - 4.32)), previous dusty working environment (AOR=2.26, 95% CI, (1.07 - 4.78)), ever smoking (AOR 3.66, 95%CI (1.05 - 12.72)) and service year (AOR = 1.86, 95 % CI = (1.16 – 2.99)) showed statistically significant association with chronic respiratory symptoms among pharmaceutical factory workers.
Conclusion and recommendation: previous history of respiratory diseases, family history of chronic respiratory diseases, previous dusty working environment, ever cigarette smoking, and service year were determinants of chronic respiratory symptoms of the workers in pharmaceutical factory. Public health endeavors to prevent the burden of chronic respiratory symptoms in the pharmaceutical factories should target reduction of adverse workplace exposures and discouragement of ever smoking.
Key word: Chronic respiratory symptoms, socio demographic, behavioral, environmental and occupational factors and pharmaceutical factory worker.
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Chronic respiratory symptoms, socio demographic, behavioral, environmental and occupational factors and pharmaceutical factory worker.