Patterns of Diabetic Retinopathy Predicting Diabetic Kidney Disease Severity ,at Tikur Anbessa Specialized Hospital (TASH),College of Health Sciences, Addis Ababa University.
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Date
2021-12
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Addis Abeba University
Abstract
Background: Diabetic retinopathy and diabetic kidney disease are microvascular complications
of diabetes mellitus. Patients with diabetic retinopathy are prone to develop diabetic kidney
disease. However, there is limited evidence on the relationship between diabetic retinopathy
stages and diabetic kidney disease severity.
Objective: To identify the relationship between patterns of diabetic retinopathy and diabetic
kidney disease
Methods: A hospital based cross-sectional study was conducted at diabetes clinic of TASH,
Ethiopia from June 2021 to July 2021. Structured questionnaire, patients’ charts and/or electronic
medical records were used to collect data among 101 diabetic patients with diabetic retinopathy
aged 18 years and above. Data were cleaned, coded and entered into IBM SPSS version 26
software for analysis. Descriptive and logistic regression analyses were used and P-value < 0.05
was used as statistically significant.
Results: The mean (±SD) age of the participants was 52.9 (±11.8) years. Majority (94.1%) of
our diabetic retinopathy patients had nonproliferative retinopathy and 70.3% of diabetic
retinopathy patients had concomitant diabetic kidney disease. In multivariable logistic regression
analyses, diabetic retinopathy severity (severe nonproliferative diabetic retinopathy to
proliferative diabetic retinopathy vs. mild to moderate nonproliferative diabetic retinopathy)
[AOR= 3.97; 95% CI: 1.01 - 15.62], T2DM [AOR= 3.74; 95% CI: 1.29 - 10.75], presence of
CVD [AOR= 3.18; 95% CI: 1.05- 9.59] were the independent predictors of diabetic kidney
disease.
Conclusions: In this study, diabetic retinopathy severity was strongly associated with diabetic
kidney disease. Therefore, evaluation of diabetic retinopathy severity at the time of retinal
screening is recommended.
Budget grant: Addis Ababa University (AAU), College of Health Sciences, School of Medicine
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Keywords
Diabetic retinopathy, Diabetic kidney disease, TASH, Ethiopia