Demography and Clinico-pathologic Pattern of Laryngeal Cancer at Tikur Anbessa Specialized Hospital: A Retrospective Cross Sectional Study
| dc.contributor.advisor | Abreha, Ayenalem (MD, Internist, Consultant clinical oncologist) | |
| dc.contributor.advisor | Jemal, Ahmedin(DVM, PHD) | |
| dc.contributor.advisor | Dr. Kantelhardt, Eva Johanna | |
| dc.contributor.author | Eshetu, Natenael | |
| dc.date.accessioned | 2021-06-13T08:52:45Z | |
| dc.date.accessioned | 2023-11-05T09:35:06Z | |
| dc.date.available | 2021-06-13T08:52:45Z | |
| dc.date.available | 2023-11-05T09:35:06Z | |
| dc.date.issued | 2021-04 | |
| dc.description.abstract | Background: Malignant laryngeal tumors are uncommon, yet invariably fatal neoplasms of the larynx. Late presentation of the disease may worsen management outcomes. Although the incidence of malignant tumors of the larynx is increasing in developing countries, like Ethiopia, there is a lack of evidence regarding the overall profile of laryngeal cancers in Ethiopia. Objectives: To assess the epidemiologic, clinico-histo-pathologic characteristics of laryngeal patients attending at oncology department of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods: A 3-year retrospective cross-sectional review of medical records of patients managed for malignant laryngeal tumors at the oncology department of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia, was performed. The demographic, clinical & histopathologic characteristics of participants were computed by using descriptive statistics (mean, percentage, frequencies, and standard deviation). Finally, the study finding was presented using diagrams, tables, and figures. Results: Most of the laryngeal cancer patients who attended the oncology unit of Tikur Anbessa Specialized Hospital are elderly males, with a male to female ratio of 5.1:1, and the sixth decade being the most affected age stratum. The most common presenting symptom was dysphonia. The majority (88.8%) of patients presented with late stage of the disease and squamous cell carcinoma is by far the most common histopathology, occurring in 98.8% of the patients. Conclusion: Elderly men are the most affected age group of laryngeal neoplasms. Late disease presentation observed in the patients can lead to poor management outcomes and limited management options. Health education of the community on early features of laryngeal cancer, early symptom detection by clinicians, and policies targeted at reducing cigarette smoking and alcohol consumption is recommended. | en_US |
| dc.identifier.uri | http://etd.aau.edu.et/handle/123456789/26807 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Addis Ababa University | en_US |
| dc.subject | Laryngeal Cancer ,Demography | en_US |
| dc.title | Demography and Clinico-pathologic Pattern of Laryngeal Cancer at Tikur Anbessa Specialized Hospital: A Retrospective Cross Sectional Study | en_US |
| dc.type | Thesis | en_US |