Radiological-pathological correlation of ACR-TIRADS ultrasound classification of thyroid nodules with fine needle aspiration cytology results at TikurAnbessa Specialized Hospital: Prospective study from April 2023- November 2023
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Date
2023-11
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Addis Ababa University
Abstract
Background:Ultrasound based risk stratification is a widely used method currently helping to guide
management in patients with thyroid nodules; which are common and mostly benign. The use of
these risk stratification methods has helped reduce unnecessary FNAC rates, therefore, reducing
the burden both on patients and the health care system. This study aims to determine the
effectiveness of ultrasound-based risk stratification by correlating ultrasound findings and
pathologic diagnosis at TikurAnbessa specialized hospital (TASH).
Methodology:This was a hospital based prospective radiologic pathologic correlation study in patients referred
for ultrasound guided FNAC based on their American College of Radiology Thyroid Imaging,
Reporting and Data System (ACR-TIRADS) score at TikurAnbessa Specialized Referral and
Teaching Hospital, radiology department, during the time period of April-September 2023 to
assess accuracy of ACR-TIRADS in ultrasound based thyroid nodule risk stratification in our
hospital.
Sixty two patients with thyroid nodules were subjected to ultrasound and USG guided FNAC.
Each was assigned a TIRADS and Bethesda category. The outcomes were contrasted in order to
assess the ultrasound's sensitivity, specificity, and positive predictive value (PPV) in terms of
distinguishing benign from malignant nodules.
RESULT: Twenty-six of the sixty-two nodules that were analyzed classified into TIRADS 3, and
thirteen and twenty-three, respectively, into TIRADS 4 and 5. On FNAC, 36 were found to be
Bethesda 2 & 5, 7, 1 and 8 to Bethesda 3, 4, 5 and 6 respectively. The sensitivity, specificity and
PPV of ultrasound were found to be 93.75, 54.35, and 41.67 % respectively.
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Keywords
Thyroid nodule, Ultrasound, ACR-TIRADS, FNAC, pathologic diagnosis, effectiveness/accuracy