Estimating the Health Burden and Status of Rabies in Animals and Humans From 2014-2019 In Addis Ababa, Ethiopia

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Addis Ababa University


Rabies is a notoriously underreported and neglected disease of low-income countries like Ethiopia where financial resources are limited and numerous interests compete, there is a need for updated quantitative data on the public awareness, health burden and costs of diseases to support prioritization. The aim of this study was to determine the level of community knowledge, Attitude and Practices (KAP) regarding rabies and to estimate the health burden and post-exposure treatment (PET) costs of rabies in Addis Ababa. Hospital based cross-sectional study was conducted from February 2020 to April 2020 to assess the KAP towards rabies. Two hundred and sixty-seven people who were bitten by rabies suspected animals were purposively interviewed for this study and retrospective study was conducted to assess the burden of rabies over the period of six years (2014 to 2019). Based on the collected data PET costs were evaluated and the health burden was estimated in Disability-Adjusted Life Years (DALYs). The KAP study showed that 62.8% of the respondents had good level of knowledge and had medium (51.1%) level of attitude and practices towards rabies. In this study the good scores were higher in males (62.87%) than females. There was strong association between knowledge scores and type of employment (P= 0.003), Attitude and Practice scores and gender (P=0.001). There was significant positive correlation between Knowledge and Attitude and practice (P=0.001). The retrospective data indicated that a total of 8613 victims were registered and received post exposure vaccine in Addis Ababa over the period of six years (2014 to 2019). From this most important animal species responsible for PEP was dogs (93.8%). The annual suspected rabid dog exposures were estimated, and higher exposure was recorded in 2019 which was 54.5 per 100,000 populations. An annual estimate of approximately 10 human deaths and 57 disabilities resulting 430-955 DALYS per 100,000 populations per year due to administration of nerves tissue vaccine (NTV). Costs per completed (PET) estimated around 9.2 ±22.8 USD for children and 11.8±27 USD for adults in Addis Ababa.



Addis Ababa, Attitude, Community, DALYS, Knowledge, Practice, Rabies