Recurrence Rate of Differentiated Thyroid Cancer in Patients Underwent Post-Radioactive Iodine Ablation Therapy at The Service De Medecine Nucleaire, Centre Hospital Universitaire De Bab El Oued, Algiers, Algeria

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Date

2025-05-09

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Addis Ababa University

Abstract

Introduction: Differentiated thyroid cancer (DTC) is primarily derived from follicular cells and accounts for over 90% of thyroid malignancies. Despite a high disease-free survival rate (98%) following radioactive iodine (RAI) ablation therapy, recurrence rates vary significantly globally. Objective: This study aimed to assess the recurrence rate of DTC through a retrospective cross sectional analysis of patients who underwent RAI therapy. Methods: A sample size of 100 patients with DTC treated at the Service de Médecine Nucléaire was analyzed using specific inclusion/exclusion criteria. Result: The recurrence rate post-RAI therapy was 11% with 6/11(55%) cytological confirmed and 5/11(45%) not confirmed. The study show no associated risk factor for recurrence. Conclusion: the study shows recurrence rate was in the low-risk group but higher than the local region. No predictor associate with recurrence. Recommendation: revise management principle and risk stratification. PET/CT must be included in the follow-up

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Keywords

Differentiated thyroid cancer, Radioactive Iodine, recurrence

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